Title:
MULTIFUNCTIONAL METAL NANOSTRUCTURE AND METHOD FOR PRODUCING SAME
Document Type and Number:
WIPO Patent Application WO/2015/056766
Kind Code:
A1
Abstract:
Provided is a stabilized metal nanostructure that does not aggregate when surface-modified by a functional molecule that reacts with a biomolecule. A metal nanostructure is 30-90% covered by at least one type of colloid-stabilized functional molecule, and the metal nanostructure is further covered by one or more types of biologically functional molecule.
Inventors:
ICHIKAWA YUKI (JP)
SHIBA KIYOTAKA (JP)
SHIBA KIYOTAKA (JP)
Application Number:
PCT/JP2014/077633
Publication Date:
April 23, 2015
Filing Date:
October 17, 2014
Export Citation:
Assignee:
AISIN SEIKI (JP)
JAPAN FOUND CANCER (JP)
JAPAN FOUND CANCER (JP)
International Classes:
G01N33/543; A61K41/00; A61K47/48; A61K49/00; B22F1/00; B22F1/02
Foreign References:
| US20120225021A1 | 2012-09-06 | |||
| US20120225021A1 | 2012-09-06 |
Other References:
YUKIO NAGASAKI ET AL.: "PEG/Tanpakushitsu Misseiso o Yusuru Kin Nano Ryushi no Sekkei to Kino", SYMPOSIUM ON MACROMOLECULES YOKOSHU, vol. 54, no. 2, 5 September 2005 (2005-09-05), pages 3040 - 3041, XP008183089
CHRISTINA M. ET AL.: "Polymer-coated surface enhanced Raman scattering(SERS) gold nanoparticles for multiplexed labeling of chronic lymphocytic leukemia cells", PROGRESS IN BIOMEDICAL OPTICS AND IMAGING, vol. 8212, 2012, pages 821203.1 - 821203.11, XP060023160
TIANQING LIU ET AL.: "A solution to the PEG Dilemma: Efficent Bioconjugation of Large Gold Nanoparticles for Biodiagnostic Applications using Mixed Layers", LANGMUIR, vol. 28, no. 44, pages 15634 - 15642, XP055339707
See also references of EP 3059589A4
G. LUO ET AL., INTERNATIONAL JOURNAL OF PHARMACEUTICS, vol. 385, 2010, pages 150 - 156
G. F. PACIOTTI ET AL., DRUG DELIVERY, vol. 11, 2004, pages 169 - 183
K. A. KELLY ET AL., PLOS MEDICINE, vol. 5, no. 4, 2008, pages E45
S.J. SHIN ET AL., PNAS, vol. 110, no. 48, 2013, pages 19414 - 19419
CHRISTINA M. ET AL.: "Polymer-coated surface enhanced Raman scattering(SERS) gold nanoparticles for multiplexed labeling of chronic lymphocytic leukemia cells", PROGRESS IN BIOMEDICAL OPTICS AND IMAGING, vol. 8212, 2012, pages 821203.1 - 821203.11, XP060023160
TIANQING LIU ET AL.: "A solution to the PEG Dilemma: Efficent Bioconjugation of Large Gold Nanoparticles for Biodiagnostic Applications using Mixed Layers", LANGMUIR, vol. 28, no. 44, pages 15634 - 15642, XP055339707
See also references of EP 3059589A4
G. LUO ET AL., INTERNATIONAL JOURNAL OF PHARMACEUTICS, vol. 385, 2010, pages 150 - 156
G. F. PACIOTTI ET AL., DRUG DELIVERY, vol. 11, 2004, pages 169 - 183
K. A. KELLY ET AL., PLOS MEDICINE, vol. 5, no. 4, 2008, pages E45
S.J. SHIN ET AL., PNAS, vol. 110, no. 48, 2013, pages 19414 - 19419
Attorney, Agent or Firm:
SATO & ASSOCIATES (JP)
Patent business corporation creation international patent firm (JP)
Patent business corporation creation international patent firm (JP)
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