Title:
MULTIFUNCTIONALIZED POLYETHYLENE GLYCOL DERIVATIVE AND PREPARATION METHOD THEREFOR
Document Type and Number:
WIPO Patent Application WO/2016/050210
Kind Code:
A1
Abstract:
Disclosed are a multifunctionalized polyethylene glycol derivative and a preparation method therefor. The derivative has an H-shaped structure as represented by formula (1) and comprises one linear core LPEG and four PEG branch chains, where n1, n2, n3, and n4 respectively are the degrees of polymerization of the branch chains, U1 and U2 are trivalent branching groups connecting the core LPEG to two of the PEG branch chains, F1 and F2 contain a functional group or a protected form R01 thereof and may or may not contain a branched group G, correspondingly, the number of R01 is one or more, F1 and F2 are either identical or different, any one linking group in the molecule or any linking group formed with an adjacent heteroatom group can either remain stable or be degraded, and any one PEG segment in the molecule is discretely polydispersed or monodispersed. The multifunctional polyethylene glycol is flexible and diverse in terms of branch structures and the lengths of branching arms, has various parameters and performance indicators that are adjustable and easy to control, and has a broad applicability.
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Inventors:
WENG WENGUI (CN)
LIU CHAO (CN)
YAN CE (CN)
WU SHAOFENG (CN)
ZHOU CHUN (CN)
LIU CHAO (CN)
YAN CE (CN)
WU SHAOFENG (CN)
ZHOU CHUN (CN)
Application Number:
PCT/CN2015/091193
Publication Date:
April 07, 2016
Filing Date:
September 30, 2015
Export Citation:
Assignee:
XIAMEN SINOPEG BIOTECH CO LTD (CN)
International Classes:
C08G65/323; C08G65/08; C08G65/334
Domestic Patent References:
| WO2012158622A2 | 2012-11-22 | |||
| WO2011123031A1 | 2011-10-06 | |||
| WO2013147015A1 | 2013-10-03 |
Foreign References:
| CN103881084A | 2014-06-25 | |||
| CN104530417A | 2015-04-22 |
Attorney, Agent or Firm:
LINDA LIU & PARTNERS (CN)
北京林达刘知识产权代理事务所(普通合伙） (CN)
北京林达刘知识产权代理事务所(普通合伙） (CN)
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