Title:
MULTILAYER STRUCTURE USING CHEMICALLY CROSSLINKED ALGINIC ACID
Document Type and Number:
WIPO Patent Application WO/2022/145419
Kind Code:
A1
Abstract:
There has been required a novel and practicable multilayer structure that has enhanced structure stability and, therefore, is improved in the enlargement of device size, easiness in processing, etc. A structure according to the present invention that comprises a core layer containing a pharmacological ingredient embedded in a chemically crosslinked alginic acid, a cationic polymer layer coating the core layer, and an anionic polymer layer coating the cationic polymer layer.
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Inventors:
FURUSAKO SHOJI (JP)
TSUDA NAOTO (JP)
TSUDA NAOTO (JP)
Application Number:
PCT/JP2021/048566
Publication Date:
July 07, 2022
Filing Date:
December 27, 2021
Export Citation:
Assignee:
MOCHIDA PHARM CO LTD (JP)
International Classes:
A61K35/12; A61L27/44; A61L27/20; A61L27/34; A61L27/38; A61L27/50; A61L27/58
Domestic Patent References:
| WO2019240219A1 | 2019-12-19 | |||
| WO2001052871A1 | 2001-07-26 | |||
| WO2014171842A1 | 2014-10-23 | |||
| WO2018151186A1 | 2018-08-23 | |||
| WO1998049202A1 | 1998-11-05 | |||
| WO2010139061A1 | 2010-12-09 | |||
| WO2019240219A1 | 2019-12-19 | |||
| WO2019168058A1 | 2019-09-06 | |||
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BIOORGANIC & MEDICINAL CHEMISTRY, vol. 11, 2003, pages 4189 - 4206
BIOMATERIALS, vol. 26, no. 34, 2005, pages 6846 - 52
AMERICAN DIABETES ASSOCIATION 60TH SCIENTIFIC SESSIONS, no. 448, 2000
CHIKAKO YOMOTA, BULL. NATL. HEALTH SCI., vol. 117, 1999, pages 135 - 139
CHIKAKO YOMOTA, BULL. NATL. INST. HEALTH SCI., vol. 121, 2003, pages 30 - 33
APPL MICROBIOL BIOTECHNOL, vol. 40, 1994, pages 638 - 643
MARUZEN: "Experimental Chemistry", vol. 16, 2007, article "Synthesis IV of Organic Compounds, Carboxylic Acids and Derivatives, Esters", pages: 35 - 70
ACID AMIDES AND ACID IMIDES, pages 118 - 154
AMINO ACIDS/PEPTIDES, 2007, pages 258 - 283
GREENE: "Protective Groups in Organic Synthesis", 2007, JOHN WILEY & SONS
JOURNAL OF THE AMERICA CHEMICAL SOCIETY, vol. 126, no. 46, 2004, pages 15046 - 15047
ORGANOMETALLICS, vol. 29, no. 23, 2010, pages 6619 - 6622
BIOORGANIC & MEDICINAL CHEMISTRY, vol. 23, no. 22, 2015, pages 7150 - 7157
ORG. PROCESS RES. DEV., vol. 22, 2018, pages 108 - 110
"Strategic Applications of Named Reactions in Organic Synthesis", 2005, ACADEMIC PRESS
STAHLWERMUTH: "Handbook of Pharmaceutical Salts: Properties, Selection, and Use", 2002, WILEY-VCH
ORGANIC LETTERS, vol. 19, no. 23, 2017, pages 6400 - 6403
CAS, no. 108468-00-4
BIOORGANIC & MEDICINAL CHEMISTRY, vol. 11, 2003, pages 4189 - 4206
Attorney, Agent or Firm:
KOBAYASHI Hiroshi et al. (JP)
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