Title:
MULTILAYER TABLET CONTAINING TELMISARTAN AND HYDROCHLOROTHIAZIDE
Document Type and Number:
WIPO Patent Application WO/2014/119767
Kind Code:
A1
Abstract:
Provided is a stable multilayer tablet containing telmisartan and hydrochlorothiazide, which is suppressed in decomposition of hydrochlorothiazide during storage, or the like. Provided is a multilayer tablet which comprises: a first layer that contains telmisartan, meglumine and a moisture-absorbing substance; and a second layer that contains hydrochlorothiazide. The moisture-absorbing substance may be a porous moisture-absorbing substance. The porous moisture-absorbing substance may be selected from among light anhydrous silicic acid, synthetic aluminum silicate, natural aluminum silicate, calcium silicate, magnesium silicate, magnesium aluminosilicate, magnesium aluminometasilicate, hydrated silicon dioxide and silicon dioxide.
Inventors:
IZUI WATARU (JP)
OGAWA YOSHIYUKI (JP)
KATSUMOTO MAMI (JP)
HIZAKI MASAYA (JP)
OGAWA YOSHIYUKI (JP)
KATSUMOTO MAMI (JP)
HIZAKI MASAYA (JP)
Application Number:
PCT/JP2014/052361
Publication Date:
August 07, 2014
Filing Date:
January 31, 2014
Export Citation:
Assignee:
SAWAI SEIYAKU KK (JP)
International Classes:
A61K31/549; A61K9/20; A61K31/4184; A61K47/02; A61K47/04; A61K47/18; A61P7/10; A61P9/12; A61P43/00
Foreign References:
| IN2892CH2009A | ||||
| JP2008524136A | 2008-07-10 | |||
| JP2005514439A | 2005-05-19 | |||
| JP2006502194A | 2006-01-19 | |||
| JP2009517366A | 2009-04-30 |
Other References:
IYAKUHIN TENKABUTSU JITEN, 2007, pages 253, XP008180557
See also references of EP 2952196A4
See also references of EP 2952196A4
Attorney, Agent or Firm:
Takahashi, Hayashi and Partner Patent Attorneys, Inc. (JP)
Patent business corporation Takahashi and wood and partners (JP)
Patent business corporation Takahashi and wood and partners (JP)
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