Title:
MULTIPLEX PCR PRIMER SET FOR SIMULTANEOUS DIAGNOSIS OF MYCOBACTERIUM TUBERCULOSIS OR NON-TUBERCULOUS MYCOBACTERIA, AND COMPOSITION AND KIT COMPRISING SAME
Document Type and Number:
WIPO Patent Application WO/2018/012896
Kind Code:
A1
Abstract:
The present invention relates to a multiplex PCR primer set capable of specifically amplifying a gene specifically existing in a Beijing family of Mycobacterium tuberculosis, and a gene capable of simultaneously diagnosing Mycobacterium tuberculosis and non-tuberculous mycobacteria, a composition and a kit comprising the primer set for simultaneous detection and discrimination of Mycobacterium tuberculosis and non-tuberculous mycobacteria, and a method for simultaneously detecting and discriminating Mycobacterium tuberculosis and non-tuberculous mycobacteria, comprising the primer set. Use of the primer set for simultaneous detection and discrimination of Mycobacterium tuberculosis and non-tuberculous mycobacteria of the present invention shows the effect of allowing for the effective discrimination of a Beijing family of Mycobacterium tuberculosis pandemic, with the concomitant discrimination and identification of clinically significant non-tuberculous mycobacteria (NTM) and Mycobacterium tuberculosis (MTBC).
Inventors:
SHIN SUNG JAE (KR)
CHAE HAN SONG (KR)
HAN SEUNG JUNG (KR)
CHO SANG NAE (KR)
CHAE HAN SONG (KR)
HAN SEUNG JUNG (KR)
CHO SANG NAE (KR)
Application Number:
PCT/KR2017/007507
Publication Date:
January 18, 2018
Filing Date:
July 13, 2017
Export Citation:
Assignee:
QURATIS INC (KR)
International Classes:
C12Q1/68
Domestic Patent References:
| WO2014148817A1 | 2014-09-25 | |||
| WO2010030049A1 | 2010-03-18 |
Foreign References:
| US20130210005A1 | 2013-08-15 | |||
| JP2012214407A | 2012-11-08 |
Other References:
PARK: "Characterization of a novel antigen of Mycobacterium tuberculosis K strain and its use in immunodiagnosis of tuberculosis", JOURNAL OF MICROBIOLOGY, vol. 52, no. 10, 2014, pages 871 - 878, XP035400730, DOI: doi:10.1007/s12275-014-4235-5
Attorney, Agent or Firm:
KIM, Soon Woong (KR)
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