Title:
MULTISPECIFIC ANTIGEN-BINDING MOLECULE HAVING BLOOD COAGULATION FACTOR VIII (FVIII) COFACTOR FUNCTION-SUBSTITUTING ACTIVITY, AND PHARMACEUTICAL FORMULATION CONTAINING SAID MOLECULE AS ACTIVE INGREDIENT
Document Type and Number:
WIPO Patent Application WO/2019/065795
Kind Code:
A1
Abstract:
The inventor has succeeded in discovering a bispecific antibody that raises FVIII cofactor function-substituting activity without raising FIX activated inhibitory activity.
Inventors:
TERANISHI YURI (JP)
KATO KAZUKI (JP)
KOGA HIKARU (JP)
IGAWA TOMOYUKI (JP)
YAMAGUCHI KAZUKI (JP)
SOEDA TETSUHIRO (JP)
KATO KAZUKI (JP)
KOGA HIKARU (JP)
IGAWA TOMOYUKI (JP)
YAMAGUCHI KAZUKI (JP)
SOEDA TETSUHIRO (JP)
Application Number:
PCT/JP2018/035832
Publication Date:
April 04, 2019
Filing Date:
September 27, 2018
Export Citation:
Assignee:
CHUGAI PHARMACEUTICAL CO LTD (JP)
International Classes:
C12N15/13; A61K39/395; A61P7/04; C07K16/36; C07K16/46; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12P21/08
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See also references of EP 3690050A4
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