Title:
MULTIVALENT LYMPHOTOXIN BETA RECEPTOR AGONISTS AND THERAPEUTIC USES THEREOF
Document Type and Number:
WIPO Patent Application WO2004058191
Kind Code:
A3
Abstract:
Multivalent antibody constructs that are specific for the human lymphotoxin beta receptor, as well as their use in treating cancer and inhibiting tumor volume in a subject are disclosed.
Inventors:
GARBER ELLEN (US)
BAILLY VERONIQUE (US)
BROWNING JEFFREY L (US)
BAILLY VERONIQUE (US)
BROWNING JEFFREY L (US)
Application Number:
PCT/US2003/041393
Publication Date:
December 29, 2005
Filing Date:
December 22, 2003
Export Citation:
Assignee:
BIOGEN IDEC INC (US)
GARBER ELLEN (US)
BAILLY VERONIQUE (US)
BROWNING JEFFREY L (US)
GARBER ELLEN (US)
BAILLY VERONIQUE (US)
BROWNING JEFFREY L (US)
International Classes:
A61K6/00; A61K39/395; A61P35/00; C07K16/28; C12N15/12; C12N15/13; A61K; (IPC1-7): C07K15/06; C12N15/12; A61K37/02
Domestic Patent References:
| WO1994013808A2 | 1994-06-23 | |||
| WO1996022788A1 | 1996-08-01 |
Other References:
BROWNING ET AL: "Characterization of surface lymphotoxin forms. Use of specific monoclonal antibodies and soluble receptors.", JOURNAL OF IMMUNOLOGY., vol. 154, no. 1, January 1995 (1995-01-01), pages 33 - 46, XP002018575
See also references of EP 1583503A4
See also references of EP 1583503A4
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