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Title:
MUSCLE ATROPHY INHIBITOR CONTAINING QUERCETIN GLYCOSIDE
Document Type and Number:
WIPO Patent Application WO/2015/166887
Kind Code:
A1
Abstract:
 The purpose of the present invention is to provide a novel muscle atrophy inhibitor containing an ingredient that can be taken safely over an extended period of time. It was discovered that a glycoside of quercetin, which is a type of polyphenol contained in plants and the like, has an inhibitory effect on the expression of myostatin which is involved in muscle atrophy. The present invention provides a novel muscle atrophy inhibitor containing quercetin glycoside, the muscle atrophy inhibitor having exceptional bioavailability and high safety.

Inventors:
OTSUKA, Yuta (1-1-1 Wakayamadai, Shimamoto-cho, Mishima-gu, Osaka 03, 〒6188503, JP)
EGAWA, Kahori (1-1-1 Wakayamadai, Shimamoto-cho, Mishima-gu, Osaka 03, 〒6188503, JP)
KANZAKI, Noriyuki (1-1-1 Wakayamadai, Shimamoto-cho, Mishima-gu, Osaka 03, 〒6188503, JP)
Application Number:
JP2015/062533
Publication Date:
November 05, 2015
Filing Date:
April 24, 2015
Export Citation:
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Assignee:
SUNTORY HOLDINGS LIMITED (1-40, Dojimahama 2-chome Kita-ku, Osaka-sh, Osaka 03, 〒5308203, JP)
International Classes:
A61K31/7048; A61P21/00; A61P43/00
Domestic Patent References:
WO2011108487A12011-09-09
WO2013053795A12013-04-18
WO2011043827A12011-04-14
Foreign References:
JP2008156294A2008-07-10
JP2012012327A2012-01-19
JP2009007313A2009-01-15
Other References:
AKIKO KOHARA ET AL.: "Datsu Soshokukei Danshi - Dansei Oen Sozai Kenkyu Development of EMR combined protein for muscle hypertrophy", FOOD STYLE 21, vol. 15, no. 9, 2011, pages 48 - 50, XP008185585
SOKOLOVA V. E. ET AL.: "Farmakologiya I Toksikologiya(Moscow", ANABOLIC ACTION OF FLAVONOIDS, vol. 41, no. 3, 1978, pages 323 - 327, XP008185279
See also references of EP 3138570A4
Attorney, Agent or Firm:
ONO, Shinjiro et al. (YUASA AND HARA, Section 206 New Ohtemachi Bldg., 2-1, Ohtemachi 2-chome, Chiyoda-k, Tokyo 04, 〒1000004, JP)
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