MUTANT HUMAN FACTOR IX WITH AN INCREASED RESISTANCE TO INHIBITION BY HEPARIN

Title:

MUTANT HUMAN FACTOR IX WITH AN INCREASED RESISTANCE TO INHIBITION BY HEPARIN

Document Type and Number:

WIPO Patent Application WO2002040544

Kind Code:

A9

Abstract:

The present invention is related to a novel composition of matter and methods of using the same. More particularly, the invention describes mutant human factor IX which has an increased resistance to inhibition by heparin. Methods of making and using this composition for the therapeutic intervention of hemophilia are disclosed.

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Inventors:

SHEEHAN JOHN P (US)

Application Number:

PCT/US2001/047276

Publication Date:

May 01, 2003

Filing Date:

November 13, 2001

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Assignee:

UNIV TEXAS (US)
SHEEHAN JOHN P (US)

International Classes:

C07K14/745; C12N9/64; C12N15/57; (IPC1-7): C12N15/57; C12N9/64; C12N5/10; A61K38/36

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