Title:
MUTANT IL-15 COMPOSITIONS AND METHODS THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/280307
Kind Code:
A9
Abstract:
Provided is modified immune cells expressing a mutant IL-15 polypeptide. In some embodiments, the modified immune cell further comprises an engineered receptor such as a chimeric antigen receptor (CAR). Also provided methods and pharmaceutical compositions for cancer treatment using the modified immune cells described herein
Inventors:
ZENG MING (CN)
ZHANG HUIHUI (CN)
LI ZHIGANG (CN)
FAN XIAOHU (CN)
YANG SHUAI (CN)
TU XIAOJIE (CN)
WU SHU (CN)
ZHANG HUIHUI (CN)
LI ZHIGANG (CN)
FAN XIAOHU (CN)
YANG SHUAI (CN)
TU XIAOJIE (CN)
WU SHU (CN)
Application Number:
PCT/CN2022/104638
Publication Date:
February 09, 2023
Filing Date:
July 08, 2022
Export Citation:
Assignee:
NANJING LEGEND BIOTECH CO LTD (CN)
International Classes:
C12N5/0783; A61K48/00; C07K19/00; C12N15/24
Attorney, Agent or Firm:
CHENG & PENG INTELLECTUAL PROPERTY LAW OFFICE (CN)
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