Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
MUTANT MICROORGANISM HAVING A HIGH 4-HYDROXYBUTYRIC ACID PRODUCTION CAPACITY, AND METHOD FOR PREPARING 4-HYDROXYBUTYRIC ACID USING SAME
Document Type and Number:
WIPO Patent Application WO/2013/085361
Kind Code:
A2
Abstract:
The present invention relates to a mutant microorganism having a high 4-hydroxybutyric acid production capacity and to a method for preparing 4-hydroxybutyric acid using the mutant microorganism. More particularly, the present invention relates to a mutant microorganism having a high 4-hydroxybutyric acid production capacity, in which genes for synthesizing 4-hydroxybutyric acid from succinic acid are amplified, genes in an anaplerotic pathway are amplified, and competitive genes are deleted so as to increase the 4-hydroxybutyric acid production capacity. The present invention also relates to a method for preparing 4-hydroxybutyric acid with a high yield rate by culturing the mutant microorganism under microaerobic conditions. The present invention enables the preparation of a mutant microorganism having a high 4-hydroxybutyric acid production capacity and the use of the mutant microorganism, and therefore is useful in the preparation of 4-hydroxybutyric acid with a high yield rate.

Inventors:
LEE SANG YUP (KR)
CHOI SOL (KR)
LEE JEONG WOOK (KR)
PARK SI JAE (KR)
Application Number:
PCT/KR2012/010665
Publication Date:
June 13, 2013
Filing Date:
December 07, 2012
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
KOREA ADVANCED INST SCI & TECH (KR)
International Classes:
C12N1/00
Domestic Patent References:
WO2010141920A22010-12-09
WO2010006076A22010-01-14
Foreign References:
KR101042242B12011-06-17
KR100957772B12010-05-12
Attorney, Agent or Firm:
LEE, Cheo Young (KR)
이처영 (KR)
Download PDF:
Claims: