Title:
MUTANT STRAINS OF NEOSPORA AND USES THEREOF
Document Type and Number:
WIPO Patent Application WO/2014/020291
Kind Code:
A3
Abstract:
The present invention concerns a mutant strain of Neospora spp, in which the function of the protein NcMIC3 and/or the function of the protein NcMIC1 is suppressed, and the uses thereof in a pharmaceutical composition or in a vaccine composition.
Inventors:
BOUSSEMART-PROUVOST ANNE-FRANCE (FR)
BRETON PASCAL (FR)
LAMARQUE MAULD (FR)
MORISSE-PHILIPPE SOLEN (FR)
SECHE EDOUARD (FR)
BRETON PASCAL (FR)
LAMARQUE MAULD (FR)
MORISSE-PHILIPPE SOLEN (FR)
SECHE EDOUARD (FR)
Application Number:
PCT/FR2013/051877
Publication Date:
March 27, 2014
Filing Date:
August 02, 2013
Export Citation:
Assignee:
VITAMFERO (FR)
International Classes:
C07K14/44; A61K39/00; A61K39/002
Domestic Patent References:
| WO2005072754A1 | 2005-08-11 |
Foreign References:
| EP0953641A2 | 1999-11-03 |
Other References:
DIANA MARCELA PENARETE-VARGAS ET AL: "Protection against Lethal Neospora caninum Infection in Mice Induced by Heterologous Vaccination with a mic1 mic3 Knockout Toxoplasma gondii Strain", INFECTION AND IMMUNITY, AMERICAN SOCIETY FOR MICROBIOLOGY, US, vol. 78, no. 2, February 2010 (2010-02-01), pages 651 - 660, XP002696799, ISSN: 0019-9567, [retrieved on 20091207], DOI: 10.1128/IAI.00703-09
A. NAGULESWARAN ET AL: "Neospora caninum Microneme Protein NcMIC3: Secretion, Subcellular Localization, and Functional Involvement in Host Cell Interaction", INFECTION AND IMMUNITY, vol. 69, no. 10, October 2001 (2001-10-01), pages 6483 - 6494, XP055061688, ISSN: 0019-9567, DOI: 10.1128/IAI.69.10.6483-6494.2001
A. NAGULESWARAN ET AL: "Neospora caninum Microneme Protein NcMIC3: Secretion, Subcellular Localization, and Functional Involvement in Host Cell Interaction", INFECTION AND IMMUNITY, vol. 69, no. 10, October 2001 (2001-10-01), pages 6483 - 6494, XP055061688, ISSN: 0019-9567, DOI: 10.1128/IAI.69.10.6483-6494.2001
Attorney, Agent or Firm:
GROSSET-FOURNIER, Chantal et al. (Paris, FR)
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