Title:
MYCOBACTERIUM TUBERCULOSIS ANTIGEN FOR DIFFERENTIATING ACTIVE TUBERCULOSIS WITH LATENT TUBERCULOSIS INFECTION AND APPLICATIONS THEREOF
Document Type and Number:
WIPO Patent Application WO/2017/028040
Kind Code:
A1
Abstract:
The present invention provides a mycobacterium tuberculosis antigen for differentiating active tuberculosis with latent tuberculosis infection and applications thereof. Specifically, the present invention provides an immunogenic composition, a vaccine, or a pharmaceutical composition. The comprised immunogenic components comprise the following one or more polypeptides or immune segments thereof: (a) a polypeptide formed by amino acid sequences indicated by SEQ ID No.1, SEQ ID No.2, SEQ ID No.3 or SEQ ID No.4, or an immune segment thereof; and (b) a polypeptide having at least 70% consistency with an amino acid sequence defined by (a), having same functions as those of (a) and derived from (a), or an immune segment thereof.
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Inventors:
LIU JUN (CA)
ZHANG LU (CN)
ZHANG LU (CN)
Application Number:
PCT/CN2015/087059
Publication Date:
February 23, 2017
Filing Date:
August 14, 2015
Export Citation:
Assignee:
CHENGDU YONGAN PHARM CO LTD (CN)
LIU JUN (CA)
LIU JUN (CA)
International Classes:
A61K39/04; A61P31/06; A61P35/00; C07K14/35; C12N1/21; C12N15/31
Foreign References:
| CN102439134A | 2012-05-02 | |||
| CN103760345A | 2014-04-30 |
Attorney, Agent or Firm:
BEIJING SANYOU INTELLECTUAL PROPERTY AGENCY LTD. (CN)
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