Title:
MYCOBACTERIUM TUBERCULOSIS FUSION PROTEIN, PREPARATION METHOD THEREFOR AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/078438
Kind Code:
A1
Abstract:
A mycobacterium tuberculosis (MTB) fusion protein, a preparation method therefor and a use thereof. The MTB fusion protein is composed of two proteins, EAST6 and CFP10, has six connection structures, namely EEC, ECE, CEE, ECC, CEC and CCE, may be used to prepare various diagnostic or auxiliary diagnostic products for MTB infections and NTM infections, and has relatively high sensitivity and specificity.
Inventors:
ZHANG KAIJUN (CN)
LI BINGCHAO (CN)
FU QINGSONG (CN)
SHEN YINQI (CN)
REN ZHAOYUAN (CN)
LI BINGCHAO (CN)
FU QINGSONG (CN)
SHEN YINQI (CN)
REN ZHAOYUAN (CN)
Application Number:
PCT/CN2022/130210
Publication Date:
May 11, 2023
Filing Date:
November 07, 2022
Export Citation:
Assignee:
COENBIO CO LTD (CN)
International Classes:
C07K19/00; C12N15/62; C12N15/70; G01N33/569; G01N33/68
Foreign References:
| CN113980145A | 2022-01-28 | |||
| CN110684116A | 2020-01-14 | |||
| CN111905110A | 2020-11-10 | |||
| CN113045677A | 2021-06-29 | |||
| CN110423279A | 2019-11-08 | |||
| CN107144694A | 2017-09-08 | |||
| CN101221173A | 2008-07-16 | |||
| CN107076744A | 2017-08-18 | |||
| CN111655734A | 2020-09-11 | |||
| CN107216373A | 2017-09-29 | |||
| CN107141341A | 2017-09-08 | |||
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| US20050208594A1 | 2005-09-22 | |||
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Other References:
DATABASE Protein 1 December 2020 (2020-12-01), ANONYMOUS : "Chain A, ESAT-6-like protein esxB", XP093063121, retrieved from NCBI Database accession no. 3FAV
DATABASE Protein 24 July 2018 (2018-07-24), ANONYMOUS : "Cfp-10 antigen [Mycobacterium tuberculosis variant bovis] ", XP093063123, retrieved from NCBI Database accession no. AXE75119.1
DATABASE Protein 24 July 2018 (2018-07-24), ANONYMOUS : "Cfp-10 antigen [Mycobacterium tuberculosis variant bovis] ", XP093063123, retrieved from NCBI Database accession no. AXE75119.1
Attorney, Agent or Firm:
UNITALEN ATTORNEYS AT LAW CO., LTD. (CN)
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