Title:
N-ALKYL PHENYLCARBOXAMIDE BETA-SECRETASE INHIBITORS FOR THE TREATMENT OF ALZHEIMER'S DISEASE
Document Type and Number:
WIPO Patent Application WO2005004802
Kind Code:
A3
Abstract:
The present invention is directed to compounds which are inhibitors of the beta-secretase enzyme and which are useful in the treatment or prevention of diseases in which the beta-secretase enzyme is involved, such as Alzheimer's disease. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the treatment of such diseases in which the beta-secretase enzyme is involved.
Inventors:
COBURN CRAIG A (US)
STACHEL SHAWN J (US)
VACCA JOSEPH P (US)
STACHEL SHAWN J (US)
VACCA JOSEPH P (US)
Application Number:
PCT/US2004/020234
Publication Date:
September 22, 2005
Filing Date:
June 25, 2004
Export Citation:
Assignee:
MERCK & CO INC (US)
COBURN CRAIG A (US)
STACHEL SHAWN J (US)
VACCA JOSEPH P (US)
COBURN CRAIG A (US)
STACHEL SHAWN J (US)
VACCA JOSEPH P (US)
International Classes:
A61K31/16; A61K31/18; A61K31/275; A61K31/40; A61K31/495; A61K31/50; C07C233/05; C07C237/10; C07C255/50; C07C255/57; C07C311/04; C07C311/08; C07D207/04; C07D241/04; C07D295/185; A61K; (IPC1-7): C07C311/04; A61K31/16; A61K31/18; A61K31/275; A61K31/40; A61K31/495; A61K31/50; C07C233/05; C07C255/50; C07D207/04; C07D241/04
Domestic Patent References:
| WO2003057721A2 | 2003-07-17 |
Other References:
See also references of EP 1641748A4
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