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Title:
N-ALKYL TRYPTANTHRIN DERIVATIVE, PREPARATION METHOD FOR SAME, AND APPLICATION THEREOF
Document Type and Number:
WIPO Patent Application WO/2015/007249
Kind Code:
A1
Abstract:
An N-alkyl tryptanthrin derivative, a preparation method for same, and an application thereof. The structure of the derivative is as represented by formula I. The N-alkyl tryptanthrin derivative can serve as a highly active IDO inhibitor, for use in preparing a medicament for prevention and/or treatment of a disease having a pathological characteristic of an IDO-mediated tryptophan metabolic pathway.

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Inventors:
LI HANPU (CN)
KUANG CHUNXIANG (CN)
LI JIANZHI (CN)
Application Number:
PCT/CN2014/083030
Publication Date:
January 22, 2015
Filing Date:
July 25, 2014
Export Citation:
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Assignee:
SHANGHAI TIN TSZ BIO VALLEY BIOLOG ENGINEERING CO LTD (CN)
International Classes:
C07D487/04; A61K31/519; A61K31/5377; A61P25/18; A61P25/22; A61P25/24; A61P25/28; A61P27/12; A61P31/18; A61P35/00; A61P37/00
Domestic Patent References:
WO1995013807A11995-05-26
WO2004064759A22004-08-05
WO2000018769A22000-04-06
Foreign References:
CN103570726A2014-02-12
CN103570727A2014-02-12
CA2369448A12000-10-19
JP2010248086A2010-11-04
CN102579452A2012-07-18
Attorney, Agent or Firm:
XU & PARTNERS,LLC. (CN)
上海一平知识产权代理有限公司 (CN)
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