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Title:
N-CARBOXY AMINO ACID ANHYDRIDE AND AMINO ACID CARBAMATE COMPOUND PRODUCTION METHOD
Document Type and Number:
WIPO Patent Application WO/2010/023892
Kind Code:
A1
Abstract:
Disclosed is a method of efficiently producing N-carboxy amino acid anhydride. The N-carboxy amino acid anhydride production method is characterized by including a process in which an amino acid organic salt compound and a carbonic acid diester are reacted.

Inventors:
ENDO TAKESHI (JP)
KOGA KOICHI (JP)
SUDO ATSUSHI (JP)
Application Number:
PCT/JP2009/004118
Publication Date:
March 04, 2010
Filing Date:
August 26, 2009
Export Citation:
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Assignee:
JSR CORP (JP)
ENDO TAKESHI (JP)
KOGA KOICHI (JP)
SUDO ATSUSHI (JP)
International Classes:
C07D263/44; C07C269/04; C07C271/54
Foreign References:
US20070015932A12007-01-18
JP2004269414A2004-09-30
JP2007022932A2007-02-01
JP2004269414A2004-09-30
Other References:
"Peptides, Proc. European Symp. 5th, Oxford", 1962, article H. BLOCK ET AL.: "N-CARBOXY-N-TRITYL-a-AMINO- ACID ANHYDRIDES IN PEPTIDE SYNTHESIS", pages: 83 - 87, XP002927562
JUN-ICHI YAMAGUCHI ET AL.: "Condensation of a-Amino Acid with Amine in the Absence of a Coupling Agent", CHEMISTRY LETTERS, vol. 32, no. 9, 2003, pages 830 - 831, XP008142874
JIANXIE CHEN ET AL.: "An Improved Large Scale Synthesis of the Schollkopf chiral Auxiliaries: (2R)-and (2S)-2,3-Dihydro-3,6-dimethoxy-2- isopropylpyrazine", ORGANIC PROCESS RESEARCH & DEVELOPMENT, vol. 9, 2005, pages 185 - 187, XP008142871
See also references of EP 2322515A4
Attorney, Agent or Firm:
THE PATENT CORPORATE BODY ARUGA PATENT OFFICE (JP)
Patent business corporation Alga patent firm (JP)
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