Title:
NANOLIPOPROTEIN PARTICLES AND RELATED COMPOSITIONS, METHODS AND SYSTEMS
Document Type and Number:
WIPO Patent Application WO/2009/143280
Kind Code:
A3
Abstract:
Functionalized nanolipoprotein particle presenting an anchor substrate compound for binding with a corresponding anchor compound presented on a target molecule, and related compositions methods and systems.
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Inventors:
HOEPRICH JR PAUL D (US)
FISCHER NICHOLAS O (US)
BLANCHETTE CRAIG D (US)
MASON PETER W (US)
FISCHER NICHOLAS O (US)
BLANCHETTE CRAIG D (US)
MASON PETER W (US)
Application Number:
PCT/US2009/044722
Publication Date:
December 16, 2010
Filing Date:
May 20, 2009
Export Citation:
Assignee:
L LIVERMORE NAT SECURITY LLC (US)
HOEPRICH JR PAUL D (US)
FISCHER NICHOLAS O (US)
BLANCHETTE CRAIG D (US)
MASON PETER W (US)
HOEPRICH JR PAUL D (US)
FISCHER NICHOLAS O (US)
BLANCHETTE CRAIG D (US)
MASON PETER W (US)
International Classes:
A61K47/48
Domestic Patent References:
| WO2005070400A1 | 2005-08-04 | |||
| WO2006073419A2 | 2006-07-13 |
Other References:
RENSEN P C N ET AL: "RECOMBINANT LIPOPROTEINS: LIPOPROTEIN-LIKE LIPID PARTICLES FOR DRUG TARGETING", ADVANCED DRUG DELIVERY REVIEWS, ELSEVIER BV, AMSTERDAM, NL LNKD- DOI:10.1016/S0169-409X(01)00109-0, vol. 47, 25 April 2001 (2001-04-25), pages 251 - 276, XP002273271, ISSN: 0169-409X
BIJSTERBOSCH M K ET AL: "Specific Targeting of a lipopHilic Prodrug of Iododeoxyuridine to Parenchymal Liver Cells Using Lactosylated Reconstituted High Density Lipoprotein Particles", BIOCHEMICAL PHARMACOLOGY, PERGAMON, OXFORD, GB LNKD- DOI:10.1016/0006-2952(96)00170-0, vol. 52, no. 1, 12 July 1996 (1996-07-12), pages 113 - 121, XP002568383, ISSN: 0006-2952, [retrieved on 19990308]
JASANADA F ET AL: "INDIUM-111 LABELING OF LOW DENSITY LIPOPROTEINS WITH THE DTPA-BIS(STEARYLAMIDE): EVALUATION AS A POTENTIAL RADIOPHARMACEUTICAL FOR TUMOR LOCALIZATION", BIOCONJUGATE CHEMISTRY, ACS, WASHINGTON, DC, US LNKD- DOI:10.1021/BC950073L, vol. 7, no. 1, 1 January 1996 (1996-01-01), pages 72 - 81, XP000548308, ISSN: 1043-1802
MASQUELIER M ET AL: "LOW-DENSITY LIPOPROTEIN AS A CARRIER OF ANTITUMORAL DRUGS: IN VIVO FATE OF DRUG-HUMAN LOW-DENSITY LIPOPROTEIN COMPLEXES IN MICE", CANCER RESEARCH, AMERICAN ASSOCIATION FOR CANCER REREARCH, US, vol. 46, 1 August 1986 (1986-08-01), pages 3842 - 3847, XP000827794, ISSN: 0008-5472
FISCHER NICHOLAS O ET AL: "Immobilization of His-tagged proteins on nickel-chelating nanolipoprotein particles.", BIOCONJUGATE CHEMISTRY 18 MAR 2009 LNKD- PUBMED:19239247, vol. 20, no. 3, 18 March 2009 (2009-03-18), pages 460 - 465, XP002605770, ISSN: 1520-4812
BIJSTERBOSCH M K ET AL: "Specific Targeting of a lipopHilic Prodrug of Iododeoxyuridine to Parenchymal Liver Cells Using Lactosylated Reconstituted High Density Lipoprotein Particles", BIOCHEMICAL PHARMACOLOGY, PERGAMON, OXFORD, GB LNKD- DOI:10.1016/0006-2952(96)00170-0, vol. 52, no. 1, 12 July 1996 (1996-07-12), pages 113 - 121, XP002568383, ISSN: 0006-2952, [retrieved on 19990308]
JASANADA F ET AL: "INDIUM-111 LABELING OF LOW DENSITY LIPOPROTEINS WITH THE DTPA-BIS(STEARYLAMIDE): EVALUATION AS A POTENTIAL RADIOPHARMACEUTICAL FOR TUMOR LOCALIZATION", BIOCONJUGATE CHEMISTRY, ACS, WASHINGTON, DC, US LNKD- DOI:10.1021/BC950073L, vol. 7, no. 1, 1 January 1996 (1996-01-01), pages 72 - 81, XP000548308, ISSN: 1043-1802
MASQUELIER M ET AL: "LOW-DENSITY LIPOPROTEIN AS A CARRIER OF ANTITUMORAL DRUGS: IN VIVO FATE OF DRUG-HUMAN LOW-DENSITY LIPOPROTEIN COMPLEXES IN MICE", CANCER RESEARCH, AMERICAN ASSOCIATION FOR CANCER REREARCH, US, vol. 46, 1 August 1986 (1986-08-01), pages 3842 - 3847, XP000827794, ISSN: 0008-5472
FISCHER NICHOLAS O ET AL: "Immobilization of His-tagged proteins on nickel-chelating nanolipoprotein particles.", BIOCONJUGATE CHEMISTRY 18 MAR 2009 LNKD- PUBMED:19239247, vol. 20, no. 3, 18 March 2009 (2009-03-18), pages 460 - 465, XP002605770, ISSN: 1520-4812
Attorney, Agent or Firm:
STEINFL & BRUNO et al. (Suite 810Pasadena, California, US)
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