Title:
NANOLITER FLOW RATE SEPARATION AND ELECTROSPRAY DEVICE WITH PLUG AND PLAY HIGH PRESSURE CONNECTIONS AND MULTI-SENSOR DIAGNOSTIC MONITORING SYSTEM
Document Type and Number:
WIPO Patent Application WO2008073535
Kind Code:
A9
Abstract:
A chromatography and fluidic device with connections capable of automated component changing, diagnostic leak and current sensing. The chromatography-electrospray device contains a chromatography column, a pre-column, a spray emitter, or other fluidic component imbedded within one or more inserts. The inserts are robotically placed in receiving hardware, and a "plug and play" compression fitting connection mechanism makes the fluidic seals in an automated fashion. A plurality of sensors capable of detecting leaks is situated in the device near leak- prone regions. The electrospray emitter has a current sensing electrode in proximity of the electrospray region, capable of detecting the electrospray current. In conjunction with an electronics system, these sensors allow for system and component diagnostics. The diagnostic information may then be used for manual or automated system repair.
Inventors:
VAN PELT COLLEEN K (US)
Application Number:
PCT/US2007/075817
Publication Date:
August 28, 2008
Filing Date:
August 13, 2007
Export Citation:
Assignee:
VAN PELT COLLEEN K (US)
International Classes:
B01L3/00; F16L3/00; F16L19/00; G01N1/10; G01N30/02
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