Title:
NANOPARTICLES COMPRISING IRON OXIDE PARTICLES EMBEDDED IN POLYMERIC MICELLES
Document Type and Number:
WIPO Patent Application WO/2022/112513
Kind Code:
A3
Abstract:
The present invention relates to a core-shell particle comprising a core cross-linked polymeric micelle (CCPM), and one or more iron oxide nanoparticles (IONs), wherein the one or more ION is located in the core of the CCPM. Further provided are methods for producing the core-shell particle, compositions comprising the same, the core-shell particle or the composition for use in medicine, and methods for modulating the activity of immune cells and methods of treating dysregulation of the immune system, cancer, anemia and nerve injuries.
Inventors:
HORVAT NATALIE (DE)
MUCKENTHALER MARTINA U (DE)
HENTZE MATTHIAS W (DE)
BAUER TOBIAS A (DE)
BARZ MATTHIAS (DE)
MUCKENTHALER MARTINA U (DE)
HENTZE MATTHIAS W (DE)
BAUER TOBIAS A (DE)
BARZ MATTHIAS (DE)
Application Number:
PCT/EP2021/083200
Publication Date:
July 21, 2022
Filing Date:
November 26, 2021
Export Citation:
Assignee:
EUROPEAN MOLECULAR BIOLOGY LABORATORY (DE)
UNIV HEIDELBERG (DE)
UNIV HEIDELBERG (DE)
International Classes:
A61K9/51; A61K33/26; A61P35/00
Domestic Patent References:
| WO2012040513A1 | 2012-03-29 | |||
| WO2020227620A1 | 2020-11-12 |
Foreign References:
| KR20130054676A | 2013-05-27 | |||
| US20130195755A1 | 2013-08-01 |
Attorney, Agent or Firm:
ZWICKER, Jörk (DE)
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