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Patent Searching and Data


Title:
NANOVESICLES DERIVED FROM COPROCOCCUS SP. BACTERIA, AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2019/172607
Kind Code:
A1
Abstract:
The present invention relates to vesicles derived from Coprococcus sp. bacteria, and a use thereof. The present inventors experimentally confirmed that: compared to those of a normal person, the vesicles are significantly reduced in clinical samples from patients with breast cancer, ovarian cancer, bladder cancer, myocardial infarction, cardiomyopathy and atrial fibrillation; and when the vesicles isolated from a strain are administered, the secretion of inflammatory mediators by pathogenic vesicles, such as vesicles derived from Escherichia coli, is notably inhibited. Thus, the vesicles derived from Coprococcus sp. bacteria, according to the present invention, may be usefully employed for the purpose of developing: a method for diagnosing breast cancer, ovarian cancer, bladder cancer, myocardial infarction, cardiomyopathy or atrial fibrillation; and a composition for preventing, treating or improving gastritis, stomach cancer, colitis, colorectal cancer, breast cancer, ovarian cancer, bladder cancer, myocardial infarction, cardiomyopathy, atrial fibrillation or inflammatory diseases.

Inventors:
KIM YOON-KEUN (KR)
Application Number:
KR2019/002514
Publication Date:
September 12, 2019
Filing Date:
March 05, 2019
Export Citation:
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Assignee:
MD HEALTHCARE INC (KR)
International Classes:
C12Q1/689; A23L33/135; A61K35/74; A61P35/00; A61P37/00; C12Q1/6851
Foreign References:
KR101833348B12018-03-02
US20150374760A12015-12-31
US20170020932A12017-01-26
KR20180006303A2018-01-17
KR20180018354A2018-02-21
KR20110025603A2011-03-10
Attorney, Agent or Firm:
LEE, Myoung-Jin (KR)
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