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Patent Searching and Data


Title:
NANOVESICLES DERIVED FROM METHYLOBACTERIUM SP. BACTERIA, AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2019/172597
Kind Code:
A1
Abstract:
The present invention relates to vesicles derived from Methylobacterium sp. bacteria, and a use thereof. The present inventors experimentally confirmed that: compared to those of a normal person, the vesicles are significantly reduced in clinical samples from patients with pancreatic cancer, cholangiocarcinoma, breast cancer, ovarian cancer, bladder cancer, lymphoma, myocardial infarction, cardiomyopathy, variant angina, diabetes and Parkinson's disease; and when the vesicles isolated from a strain are administered, the secretion of inflammatory mediators by pathogenic vesicles, such as vesicles derived from Escherichia coli, is notably inhibited. Thus, the vesicles derived from Methylobacterium sp. bacteria, according to the present invention, may be usefully employed for the purpose of developing: a method for diagnosing pancreatic cancer, cholangiocarcinoma, breast cancer, ovarian cancer, bladder cancer, lymphoma, myocardial infarction, cardiomyopathy, variant angina, diabetes or Parkinson's disease; and a composition for preventing, improving or treating said diseases.

Inventors:
KIM, Yoon-Keun (521-203, 70 Hanbit-ro,,Paju-Si, Gyeonggi-do, 10908, KR)
Application Number:
KR2019/002497
Publication Date:
September 12, 2019
Filing Date:
March 05, 2019
Export Citation:
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Assignee:
MD HEALTHCARE INC. (#1303, 9 World Cup buk-ro 56-gil,,Mapo-Gu, Seoul, 03923, KR)
International Classes:
C12Q1/689; C12Q1/6851; A23L33/135; A61K35/74; A61P35/00; A61P37/00
Attorney, Agent or Firm:
LEE, Myoung-Jin (6th floor, 28 Yeongdong-daero 85-gil,,Gangnam-Gu, Seoul, 06180, KR)
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