Title:
NAPHTHYRIDINE COMPOUND, PHARMACEUTICAL COMPOSITION AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2018/064852
Kind Code:
A1
Abstract:
The present invention relates to the field of biomedicine, and discloses a naphthyridine compound, a pharmaceutical composition and use thereof. The naphthyridine compound has a structure as represented by formula (I) or in the form of a stereoisomer, a geometric isomer, a tautomer, an oxynitride, a hydrate, a solvate, a metabolite, and a pharmaceutically acceptable salt or prodrug thereof. The naphthyridine compound of the present invention has significantly better anti-tumor effects than those in the prior art, and the naphthyridine compound of the present invention can be used to treat protein kinase-mediated diseases.
Inventors:
HUANG WEI (CN)
Application Number:
PCT/CN2016/105012
Publication Date:
April 12, 2018
Filing Date:
November 08, 2016
Export Citation:
Assignee:
NANJING NATINEFY PHARMATECH CO LTD (CN)
WUHAN NOVAFFEY SCIENCE & TECH CO LTD (CN)
WUHAN NOVAFFEY SCIENCE & TECH CO LTD (CN)
International Classes:
A61K31/4709; A61P9/10; A61P11/00; A61P19/00; A61P35/00; C07D471/04
Foreign References:
| CN103183674A | 2013-07-03 |
Other References:
See also references of EP 3421038A4
Attorney, Agent or Firm:
RUNPING&PARTNERS (CN)
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