Title:
NATRIURETIC POLYPEPTIDES FOR REDUCING OR PREVENTING RESTENOSIS
Document Type and Number:
WIPO Patent Application WO/2010/078325
Kind Code:
A3
Abstract:
Materials and methods related to using natriuretic polypeptides to reduce proliferation of smooth muscle cells, and to reduce or prevent restenosis.
Inventors:
BURNETT JOHN C JR (US)
CHEN HORNG H (US)
LISY ONDREJ (US)
CHEN HORNG H (US)
LISY ONDREJ (US)
Application Number:
PCT/US2009/069687
Publication Date:
October 28, 2010
Filing Date:
December 29, 2009
Export Citation:
Assignee:
MAYO FOUNDATION (US)
BURNETT JOHN C JR (US)
CHEN HORNG H (US)
LISY ONDREJ (US)
BURNETT JOHN C JR (US)
CHEN HORNG H (US)
LISY ONDREJ (US)
International Classes:
C07K14/47; A61K38/17; A61P9/10
Foreign References:
| US20050059600A1 | 2005-03-17 |
Other References:
BARBER, M. N. ET AL.: "Atrial natriuretic peptide preserves endothelial function during intimal hyperplasia.", J. VASE. RES., vol. 42, 2005, pages 101 - 110
LISY, 0. ET AL.: "Design, synthesis and actions of a novel chimeric natiruretic peptide: CD-NP.", J. AM. COLL. CARDIOL., vol. 52, no. 1, 1 July 2008 (2008-07-01), pages 60 - 68
DICKEY, D. M. ET AL.: "Novel bifunctional natriuretic peptide as potential therapeutics.", J. BIOL. CHEM., vol. 283, no. 50, 12 December 2008 (2008-12-12), pages 35003 - 35009
LISY, 0. ET AL.: "Design, synthesis and actions of a novel chimeric natiruretic peptide: CD-NP.", J. AM. COLL. CARDIOL., vol. 52, no. 1, 1 July 2008 (2008-07-01), pages 60 - 68
DICKEY, D. M. ET AL.: "Novel bifunctional natriuretic peptide as potential therapeutics.", J. BIOL. CHEM., vol. 283, no. 50, 12 December 2008 (2008-12-12), pages 35003 - 35009
Attorney, Agent or Firm:
KAYTOR, Elizabeth, N. et al. (Minneapolis, Minnesota, US)
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