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Patent Searching and Data


Title:
NDM INHIBITOR
Document Type and Number:
WIPO Patent Application WO/2013/015388
Kind Code:
A1
Abstract:
The purpose of the present invention is to provide a novel NDM (New Delhi metallo-β-lactamase) inhibitor as a drug for restoring the antibacterial activity of a β-lactam antibiotic that has been inactivated due to degradation by NDM. The present invention provides an NDM inhibitor containing a compound represented by general formula (I).

Inventors:
MORINAKA AKIHIRO (JP)
MAEBASHI KAZUNORI (JP)
IDA TAKASHI (JP)
HIKIDA MUNEO (JP)
YAMADA MOTOTSUGU (JP)
ABE TAKAO (JP)
Application Number:
PCT/JP2012/069050
Publication Date:
January 31, 2013
Filing Date:
July 26, 2012
Export Citation:
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Assignee:
MEIJI SEIKA PHARMA CO LTD (JP)
MORINAKA AKIHIRO (JP)
MAEBASHI KAZUNORI (JP)
IDA TAKASHI (JP)
HIKIDA MUNEO (JP)
YAMADA MOTOTSUGU (JP)
ABE TAKAO (JP)
International Classes:
A61K31/194; A61K31/351; A61K31/40; A61K31/407; A61K31/4164; A61K31/4406; A61K31/445; A61K31/5375; A61K45/00; A61P31/04; A61P43/00; C07C57/26; C07C57/48; C07C59/46; C07C217/22; C07D309/06
Domestic Patent References:
WO2007034924A12007-03-29
WO2007034924A12007-03-29
Foreign References:
JP2009040743A2009-02-26
Other References:
YOSHIKAZU ISHII: "Super Saikin no Shinki Yakuzai Taisei Inshi NMD-1", MEDICAL BIO, vol. 7, no. 6, 1 November 2010 (2010-11-01), pages 28 - 31, XP008172763
ANTIMICROB. AGENTS CHEMOTHE R, vol. 53, no. 12, 2009, pages 5046
JAPANESE JOURNAL OF CHEMOTH ERAPY, vol. 58, no. 6, 2010, pages 639
ANTIMICROB. AGENTS CHEMOTHE R., vol. 54, no. 11, 2010, pages 4914
See also references of EP 2737900A4
Attorney, Agent or Firm:
KATSUNUMA Hirohito et al. (JP)
Katsunuma Hirohito (JP)
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Claims: