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Title:
NERVE REGENERATION-INDUCING MATERIAL
Document Type and Number:
WIPO Patent Application WO/2017/159700
Kind Code:
A1
Abstract:
A non-tubular material for nerve regeneration induction use, which can be used for the regeneration of a damaged part in a nerve, and which comprises: (A) a crosslinked substance produced by crosslinking a low-endotoxin bioabsorbable polysaccharide having a carboxyl group in the molecule with at least one crosslinkable reagent selected from a compound represented by general formula (I) and a salt thereof via covalent bonds; and (B) a bioabsorbable polymer. R1HN-(CH2)n-NHR2 (I) [wherein R1 and R2 independently represent a hydrogen atom or a group represented by formula: -COCH(NH2)-(CH2)4-NH2, and n represents an integer of 2 to 18] Thus, a medical material that can induce the regeneration of a damaged part in a nerve is provided.

Inventors:
SUZUKI YOSHIHISA (JP)
TANIHARA MASAO (JP)
ISAJI MITSUKO (JP)
Application Number:
PCT/JP2017/010274
Publication Date:
September 21, 2017
Filing Date:
March 14, 2017
Export Citation:
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Assignee:
TAZUKE KOFUKAI (JP)
NAT UNIV CORP NARA INST OF SCIENCE AND TECH (JP)
MOCHIDA PHARM CO LTD (JP)
International Classes:
A61P25/00; A61L27/18; A61L27/20; A61L27/26; A61L27/38; A61P43/00
Domestic Patent References:
WO1993013136A11993-07-08
Foreign References:
US20050069525A12005-03-31
JP2000198738A2000-07-18
JP2002078792A2002-03-19
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JP2013165884A2013-08-29
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Other References:
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Y.SUZUKI ET AL.: "Nontubulation Repair of Peripheral Nerve Gap Using Heparin/Alginate Gel Combined with b-FGF", PRS GLOBAL OPEN, vol. 4, no. 1, January 2016 (2016-01-01), pages 1 - 3, XP055545095
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Attorney, Agent or Firm:
KOBAYASHI Hiroshi et al. (JP)
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