Title:
NEURITE ELONGATION STIMULATOR
Document Type and Number:
WIPO Patent Application WO/2010/087313
Kind Code:
A1
Abstract:
Disclosed is a novel neurite elongation stimulator. The neurite elongation stimulator comprises a compound represented by general formula (1) as an active ingredient.
In general formula (1), R1 to R3 independently represent a hydrogen atom or a proper substituent; Z1 represents a heterocyclic ring, and Z2 represents a heterocyclic ring which is the same as or different from the heterocyclic ring represented by Z1, or an aromatic ring, wherein each of the heterocyclic ring and the aromatic ring may have a substituent; o represents an integer of 0, 1 or 2, and p represents an integer of 0 or 1, wherein p is 1 when o is 0 or 2, p is 0 when o is 1, R1 and R2 do not exist when o is 0, and R3 does not exist and a carbon atom to which R2 is bound and Z2 are bound to each other through a single bond when p is 0; X1
- represents a proper counter anion; and q represents an integer of 1 or 2.
Inventors:
OHTA HITOMI (JP)
AKITA KENJI (JP)
OHTA TSUNETAKA (JP)
KAWATA TOSHIO (JP)
FUKUDA SHIGEHARU (JP)
AKITA KENJI (JP)
OHTA TSUNETAKA (JP)
KAWATA TOSHIO (JP)
FUKUDA SHIGEHARU (JP)
Application Number:
PCT/JP2010/050923
Publication Date:
August 05, 2010
Filing Date:
January 25, 2010
Export Citation:
Assignee:
HAYASHIBARA BIOCHEM LAB (JP)
OHTA HITOMI (JP)
AKITA KENJI (JP)
OHTA TSUNETAKA (JP)
KAWATA TOSHIO (JP)
FUKUDA SHIGEHARU (JP)
OHTA HITOMI (JP)
AKITA KENJI (JP)
OHTA TSUNETAKA (JP)
KAWATA TOSHIO (JP)
FUKUDA SHIGEHARU (JP)
International Classes:
A61K31/423; A61K31/352; A61K31/381; A61K31/403; A61K31/404; A61K31/4045; A61K31/4152; A61K31/4155; A61K31/4184; A61K31/42; A61K31/421; A61K31/427; A61K31/428; A61K31/44; A61K31/4425; A61K31/4439; A61K31/444; A61K31/47; A61K31/4709; A61K31/501; A61P1/14; A61P7/04; A61P9/10; A61P11/00; A61P11/16; A61P21/00; A61P21/02; A61P25/00; A61P25/02; A61P25/08; A61P25/14; A61P25/16; A61P25/18; A61P25/20; A61P25/22; A61P25/24; A61P25/28; A61P27/02; A61P27/16; A61P35/00; A61P43/00; C07D209/14; C07D209/60; C07D213/34; C07D215/12; C07D231/22; C07D235/20; C07D261/12; C07D263/32; C07D263/56; C07D277/20; C07D277/30; C07D277/36; C07D277/64; C07D277/84; C07D311/74; C07D333/64; C07D405/06; C07D413/06; C07D417/06
Domestic Patent References:
| WO2009003147A1 | 2008-12-31 | |||
| WO2007041358A2 | 2007-04-12 | |||
| WO2002090314A1 | 2002-11-14 | |||
| WO2002007781A2 | 2002-01-31 | |||
| WO2004050088A1 | 2004-06-17 | |||
| WO2003106439A1 | 2003-12-24 | |||
| WO1995005177A1 | 1995-02-23 |
Foreign References:
| JP2002121416A | 2002-04-23 | |||
| JP2005505519A | 2005-02-24 | |||
| US20030013656A1 | 2003-01-16 | |||
| JP2000355579A | 2000-12-26 | |||
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Other References:
J.BIOLOGICAL CHEMISTRY, vol. 280, no. 9, 2005, pages 7614 - 7623
BIOCHEMISTRY, vol. 45, no. 19, 2006, pages 6085 - 6094
EUROPEAN J.PHARMACOLOGY, vol. 559, no. 2-3, 2007, pages 124 - 131
BIOCHEMISTRY, vol. 45, no. 19, 2006, pages 6085 - 6094
EUROPEAN J.PHARMACOLOGY, vol. 559, no. 2-3, 2007, pages 124 - 131
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