Title:
NEURONAL DIFFERENTIATION-INDUCING PEPTIDE AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2010/117079
Kind Code:
A1
Abstract:
Disclosed is a neuronal differentiation inducer which comprises an artificially synthesized peptide comprising an amino acid sequence constituting a signal peptide in an amyloid precursor protein (APP) or a partial sequence of the amino acid sequence constituting the signal peptide.
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Inventors:
YOSHIDA TETSUHIKO (JP)
KOBAYASHI NAHOKO (JP)
KOBAYASHI NAHOKO (JP)
Application Number:
PCT/JP2010/056510
Publication Date:
October 14, 2010
Filing Date:
April 12, 2010
Export Citation:
Assignee:
TOAGOSEI CO LTD (JP)
YOSHIDA TETSUHIKO (JP)
KOBAYASHI NAHOKO (JP)
YOSHIDA TETSUHIKO (JP)
KOBAYASHI NAHOKO (JP)
International Classes:
C07K7/08; A61K38/00; A61P25/00; A61P25/16; A61P25/28; C07K19/00; C12N5/0793; C07K14/47
Foreign References:
| JPH07132033A | 1995-05-23 | |||
| JP2005330206A | 2005-12-02 |
Other References:
KANG J. ET AL.: "The precursor of Alzheimer's disease amyloid A4 protein resembles a cell- surface receptor", NATURE, vol. 325, no. 6106, 1987, pages 733 - 736
GOYAL P. ET AL.: "Phosphorylation-dependent regulation of unique nuclear and nucleolar localization signals of LIM kinase 2 in endothelial cells", J. BIOL. CHEM., vol. 281, no. 35, 2006, pages 25223 - 25230
GOYAL P. ET AL.: "Phosphorylation-dependent regulation of unique nuclear and nucleolar localization signals of LIM kinase 2 in endothelial cells", J. BIOL. CHEM., vol. 281, no. 35, 2006, pages 25223 - 25230
Attorney, Agent or Firm:
ABE MAKOTO (JP)
Makoto Abe (JP)
Makoto Abe (JP)
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