Title:
NEUROPATHY IMPROVERS CONTAINING NITROGENOUS COMPOUNDS AS THE ACTIVE INGREDIENT
Document Type and Number:
WIPO Patent Application WO/2001/010433
Kind Code:
A1
Abstract:
Compounds represented by general formula (1); and neuropathy improvers containing the same as the active ingredient: wherein G is a group represented by the general formula (G1) or the like: [wherein R?4¿ is hydrogen, acyl, or the like; W is a single bond, alkylene, or the like; m is 0 or 1; R?5¿ and R?6¿ are each hydrogen, an aliphatic hydrocarbon group, an alicyclic hydrocarbon group, an aromatic hydrocarbon group, a heterocyclic group, or the like; and R?7¿ is hydrogen, acyl, alkoxycarbonyl, or the like]; A?2¿ is a single bond, -O-, -NR?3¿-, or -S(=O)¿n?-; A?1¿ and A?3¿ are each a single bond, an aliphatic hydrocarbon group, an alicyclic hydrocarbon group, a heterocyclic group, phenylene, or the like; A?4¿ is a single bond, carbonyl, an aliphatic hydrocarbon group, or the like; and R?1¿ and R?2¿ are each hydrogen, alkyl, cycloalkyl, phenyl, a heterocyclic group, or the like, these groups being each optionally substituted.
Inventors:
SUGIURA SATOSHI (JP)
TSUTSUMI TAKAHARU (JP)
SUWA YORIMASA (JP)
ARAI TAKAMI (JP)
SAKURAI KATSUTOSHI (JP)
YOSHIOKA NOBORU (JP)
TANOKURA AKIRA (JP)
SUZUKI JUN (JP)
TSUTSUMI TAKAHARU (JP)
SUWA YORIMASA (JP)
ARAI TAKAMI (JP)
SAKURAI KATSUTOSHI (JP)
YOSHIOKA NOBORU (JP)
TANOKURA AKIRA (JP)
SUZUKI JUN (JP)
Application Number:
PCT/JP2000/005287
Publication Date:
February 15, 2001
Filing Date:
August 07, 2000
Export Citation:
Assignee:
TEIJIN LTD (JP)
SUGIURA SATOSHI (JP)
TSUTSUMI TAKAHARU (JP)
SUWA YORIMASA (JP)
ARAI TAKAMI (JP)
SAKURAI KATSUTOSHI (JP)
YOSHIOKA NOBORU (JP)
TANOKURA AKIRA (JP)
SUZUKI JUN (JP)
SUGIURA SATOSHI (JP)
TSUTSUMI TAKAHARU (JP)
SUWA YORIMASA (JP)
ARAI TAKAMI (JP)
SAKURAI KATSUTOSHI (JP)
YOSHIOKA NOBORU (JP)
TANOKURA AKIRA (JP)
SUZUKI JUN (JP)
International Classes:
A61K31/5375; A61K31/5377; A61K31/5585; A61P9/10; A61P25/28; C07C215/42; C07C233/18; C07C233/72; C07C235/30; C07D213/30; C07D213/38; C07D213/56; C07D213/74; C07D295/096; C07D295/185; C07D295/192; C07D307/91; C07D307/93; C07D309/12; C07D405/12; (IPC1-7): A61K31/133; A61K31/16; A61K31/165; A61K31/167; A61K31/215; A61K31/27; A61K31/343; A61K31/4453; A61K31/5375; A61K31/5377; A61K31/5575; A61K31/5578; C07C215/42; C07C233/18; C07C233/72; C07D213/38; C07D213/56; C07D295/08; C07D295/18; C07D307/93; C07D307/937; A61P9/10; A61P25/28
Foreign References:
| JPS6267046A | 1987-03-26 | |||
| US4128713A | 1978-12-05 | |||
| JPS5419961A | 1979-02-15 | |||
| JPS5384942A | 1978-07-26 | |||
| GB1554048A | 1979-10-17 | |||
| US4226984A | 1980-10-07 | |||
| JPH0967285A | 1997-03-11 |
Other References:
DATABASE CAPLUS ON STN AMERICAN CHEMICAL SOCIETY (ACS); KOJIMA K. ET AL.: "Synthesis and anti-platelet aggregating activity of 3-hetero analogs of (+)-9(0)-methano-.delta.6(9.alpha.)-prostaglandin I1", XP002933350
Attorney, Agent or Firm:
Maeda, Sumihiro (Intellectual Property Center 1-1,
Uchisaiwaicho 2-chom, Chiyoda-ku Tokyo, JP)
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