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Title:
NEUTRALIZING ANTIBODY AGAINST TETANUS TOXIN AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2019/210552
Kind Code:
A1
Abstract:
Provided are a neutralizing antibody against tetanus toxins, and a use thereof. The provided neutralizing antibody against tetanus toxins is capable of specifically binding to tetanus toxins, and thus has strong neutralizing activity and a high affinity, and can be used in a low amount. The provided neutralizing antibody against tetanus toxin can be used for prevention and treatment of tetanus toxin infections and for isolated antibodies of clostridium tetani-mediated diseases or disease conditions, and can also be used to diagnose and/or monitor tetanus toxin infections and isolated antibodies of clostridium tetani infections. Furthermore, the neutralizing antibody against tetanus toxin is free from foreign virus contaminations and can be widely applied to various populations.

Inventors:
LIAO, Huaxin (First to Third Floor, East of Building 6 6366 Zhuhai Avenue, Jinwan Distric, Zhuhai Guangdong 0, 519090, CN)
WANG, Yueming (First to Third Floor, East of Building 6 6366 Zhuhai Avenue, Jinwan Distric, Zhuhai Guangdong 0, 519090, CN)
YUAN, Xiaohui (First to Third Floor, East of Building 6 6366 Zhuhai Avenue, Jinwan Distric, Zhuhai Guangdong 0, 519090, CN)
ZHENG, Weihong (First to Third Floor, East of Building 6 6366 Zhuhai Avenue, Jinwan Distric, Zhuhai Guangdong 0, 519090, CN)
Application Number:
CN2018/090488
Publication Date:
November 07, 2019
Filing Date:
June 08, 2018
Export Citation:
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Assignee:
ZHUHAI TRINOMAB BIOTECHNOLOGY CO., LTD. (110 First Floor of Factory Building 6, 6366 Zhuhai Avenue Jinwan Distric, Zhuhai Guangdong 0, 519090, CN)
International Classes:
C07K16/12; A61K39/40; A61P21/02; A61P31/04; C12N15/13; G01N33/569; G01N33/577
Attorney, Agent or Firm:
BEIJING MIZAR STAR INTELLECTUAL PROPERTY AGENCY (Room 719, 6th Floor Building No.7,No.15 South College Road, Haidian District, Beijing 8, 100088, CN)
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