Title:
NEW BACTERIUM FOR PRODUCTION OF CHEMICALS AND RECOMBINANTS THEREOF
Document Type and Number:
WIPO Patent Application WO/2011/133984
Kind Code:
A3
Abstract:
Provided is an isolated novel Gram-positive Clostridium bacterium, wherein the bacterium is an anaerobic, cellulolytic and xylanolytic mesophile that produces colonies that are beige pigmented, wherein the bacterium can use carbonaceous biomass as a carbon source and can ferment sugars into ethanol, biofuels, and other chemicals. Also provided are recombinant strains of several Clostridium species wherein sporulation is disrupted. Further provided are methods of using the bacterium and strains to degrade organic material and for use in industrial processes.
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Inventors:
BOWMAN TIM (US)
ABDUL ALI MUHAMMAD (US)
HUANG KEXUE (US)
SCHMALISCH MATTHIAS (US)
ABDUL ALI MUHAMMAD (US)
HUANG KEXUE (US)
SCHMALISCH MATTHIAS (US)
Application Number:
PCT/US2011/033832
Publication Date:
May 10, 2012
Filing Date:
April 25, 2011
Export Citation:
Assignee:
QTEROS INC (US)
BOWMAN TIM (US)
ABDUL ALI MUHAMMAD (US)
HUANG KEXUE (US)
SCHMALISCH MATTHIAS (US)
BOWMAN TIM (US)
ABDUL ALI MUHAMMAD (US)
HUANG KEXUE (US)
SCHMALISCH MATTHIAS (US)
International Classes:
C12N1/21; C12N15/74; C12P7/06; C12R1/145
Other References:
DATABASE GENBANK 9 December 2003 (2003-12-09), Database accession no. AY353957
PARSHINA S. N. ET AL.: "Soehngenia saccarolytica gen. nov., sp. nov. and Clostridium amygdalinum sp. nov., two novel anaerobic, benzaldehyde- converting bacteria.", INT. J. SYST. EVOL. MICROBIOL., vol. 53, 2003, pages 1791 - 1799
SCOTCHER, M. C. ET AL.: "SpolIE regulates sporulation but does not directly affect solventogenesis in clostridium acetobutylicum ATCC 824.", J. BACTERIOL., vol. 187, no. 6, 2005, pages 1930 - 1936
LDESVAUX, M. ET AL.: "Cellulose catabolism by Clostirdium cellulolyticum growing in batch culture on defined medium.", APP. ENVIRON. MICROBIOL., vol. 66, no. 6, 2000, pages 2461 - 2470
PARSHINA S. N. ET AL.: "Soehngenia saccarolytica gen. nov., sp. nov. and Clostridium amygdalinum sp. nov., two novel anaerobic, benzaldehyde- converting bacteria.", INT. J. SYST. EVOL. MICROBIOL., vol. 53, 2003, pages 1791 - 1799
SCOTCHER, M. C. ET AL.: "SpolIE regulates sporulation but does not directly affect solventogenesis in clostridium acetobutylicum ATCC 824.", J. BACTERIOL., vol. 187, no. 6, 2005, pages 1930 - 1936
LDESVAUX, M. ET AL.: "Cellulose catabolism by Clostirdium cellulolyticum growing in batch culture on defined medium.", APP. ENVIRON. MICROBIOL., vol. 66, no. 6, 2000, pages 2461 - 2470
Attorney, Agent or Firm:
LIETO, Louis, D. et al. (650 Page Mill RoadPalo Alto, CA, US)
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