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Title:
NEW BENZOLACTAM DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME
Document Type and Number:
WIPO Patent Application WO/1998/035941
Kind Code:
A1
Abstract:
Compounds represented by general formula (I) or pharmacologically acceptable salts thereof, or hydrates of both, (wherein R?1� and R?2� are each independently a hydrogen atom, a halogen atom, etc.; R?3� is a lower alkyl group which may be substituted, an arylated lower alkyl group which may be substituted, etc.; R?4� is NHCOR?5�, NHCONR?9�R?10�, etc.; R?5� is a lower alkyl group which may be substituted; R?9� and R?10� are each independently a hydrogen atom, a lower alkyl group which may be substituted, etc.; X is CH�2?, etc.; n is 1 or 2), and medicinal compositions containing the same.

Inventors:
HAGISHITA SANJI (JP)
OKADA TETSUO (JP)
FUJIMOTO MASAFUMI (JP)
Application Number:
PCT/JP1998/000597
Publication Date:
August 20, 1998
Filing Date:
February 13, 1998
Export Citation:
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Assignee:
SHIONOGI & CO (JP)
HAGISHITA SANJI (JP)
OKADA TETSUO (JP)
FUJIMOTO MASAFUMI (JP)
International Classes:
A61K31/55; A61K31/554; A61P3/04; A61P9/00; A61P9/08; A61P9/10; A61P9/12; A61P43/00; C07D223/16; C07D225/06; C07D267/14; C07D267/22; C07D281/10; C07D281/18; C07D401/06; C07D401/12; C07D403/06; C07D403/12; C07D413/12; C07D417/12; (IPC1-7): C07D223/16; A61K31/395; A61K31/55; C07D225/06; C07D267/14; C07D281/10; C07D401/12; C07D403/04; C07D403/06; C07D403/12; C07D405/12; C07D409/12; C07D417/12
Foreign References:
JPS6115875A1986-01-23
JPH01250354A1989-10-05
JPH07165722A1995-06-27
JPS59205372A1984-11-20
JPS59172475A1984-09-29
JPS60231668A1985-11-18
Attorney, Agent or Firm:
Yamauchi, Hideaki (Sagisu 5-chome Fukushima-k, Osaka-shi Osaka, JP)
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