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Title:
NEW COMPOUNDS AS POSITIVE ALLOSTERIC MODULATORS FOR ERYTHROPOIETIN AND ERYTHROPOIETIN RECEPTOR TO TREAT ERYTHROPOIETIN DEFICIENCY DISEASES
Document Type and Number:
WIPO Patent Application WO/2017/012289
Kind Code:
A1
Abstract:
Disclosed are compounds which can act as a positive allosteric modulator for erythropoietin and erythropoietin receptor and have the activity in promoting erythropoiesis. Also disclosed are pharmaceutical compositions comprising said compounds and treatment methods utilizing said compounds.

Inventors:
WU RONG-TSUN (CN)
HORNG LIN-YEA (CN)
Application Number:
PCT/CN2016/000413
Publication Date:
January 26, 2017
Filing Date:
July 25, 2016
Export Citation:
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Assignee:
WU RONG-TSUN (CN)
International Classes:
C07H15/203; A61K31/7034; A61P7/06
Domestic Patent References:
WO2010075263A22010-07-01
WO2014158165A12014-10-02
WO2010075263A22010-07-01
WO2014158165A12014-10-02
Foreign References:
CN103156868A2013-06-19
CN101161245A2008-04-16
CN104586865A2015-05-06
Other References:
CARDULLO, NUNZIO ET AL.: "Resveratrol-Related Polymethoxystilbene Glycosides: Synthesis, Antiproliferative Activity, and Glycosidase Inhibition", JOURNAL OF NATURAL PRODUCTS, vol. 78, 5 November 2015 (2015-11-05), pages 2675 - 2683, XP055347592
MAY, L.T. ET AL., ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, vol. 47, 2007, pages 1 - 51
Attorney, Agent or Firm:
KELONG INTERNATIONAL INTELLECTUAL PROPERTY AGENCY LTD. (CN)
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