Title:
NEW CRYSTAL FORM OF NITROGEN-CONTAINING TRICYCLIC COMPOUND AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/061473
Kind Code:
A1
Abstract:
Disclosed is a new crystal form of compound 2-((5-cyclopropyl-3-(2,6-dichlorophenyl)isoxazole-4-yl)methoxy)-10H-spiro[benzo[6],7]oxazepine[3,2-b]pyridine-11,1'-cyclopropane]-7-formic acid. The new crystal form is crystal form J. Further disclosed are a pharmaceutical composition containing the crystal form J, and the use of the crystal form J or the pharmaceutical composition in the preparation of a drug for preventing, treating or relieving an FXR-mediated disease of a patient.
Inventors:
SHAN YUEFENG (CN)
CHEN LIANG (CN)
YANG XINYE (CN)
LIN JIHUA (CN)
MA FACHENG (CN)
CHEN XIAOZHOU (CN)
WANG XIAOJUN (CN)
CHEN LIANG (CN)
YANG XINYE (CN)
LIN JIHUA (CN)
MA FACHENG (CN)
CHEN XIAOZHOU (CN)
WANG XIAOJUN (CN)
Application Number:
PCT/CN2022/125324
Publication Date:
April 20, 2023
Filing Date:
October 14, 2022
Export Citation:
Assignee:
SUNSHINE LAKE PHARMA CO LTD (CN)
International Classes:
C07D491/044; A61K31/4353; A61P1/00; A61P1/16; A61P3/00; A61P3/06; A61P3/10; A61P7/02; A61P7/06; A61P9/00; A61P9/10; A61P9/12; A61P9/14; A61P15/10; A61P29/00; A61P31/20; A61P35/00
Domestic Patent References:
WO2018024224A1 | 2018-02-08 | |||
WO2021104427A1 | 2021-06-03 | |||
WO2021104421A1 | 2021-06-03 |
Foreign References:
CN112876490A | 2021-06-01 | |||
CN112876493A | 2021-06-01 |
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