Title:
NEW CRYSTAL FORM OF NITROGEN-CONTAINING TRICYCLIC COMPOUND AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/061477
Kind Code:
A1
Abstract:
A new crystal form of a nitrogen-containing tricyclic compound and a use thereof, relating to a new crystal form of 2-((5-cyclopropyl-3-(2,6-dichlorophenyl)isoxazol-4-yl)methoxy)-10H-spiro[benzo[6,7]oxazepine[3,2-b]pyridine-11,1'-cyclopropane]-7-carboxylic acid, the new crystal form being a crystal form H, and also relating to a pharmaceutical composition comprising the crystal form H, and a use of the crystal form H or the pharmaceutical composition in the preparation of a drug for preventing, treating or alleviating diseases mediated by FXR in patients.
Inventors:
CHEN LIANG (CN)
SHAN YUEFENG (CN)
YANG XINYE (CN)
WANG XIAOJUN (CN)
SHAN YUEFENG (CN)
YANG XINYE (CN)
WANG XIAOJUN (CN)
Application Number:
PCT/CN2022/125346
Publication Date:
April 20, 2023
Filing Date:
October 14, 2022
Export Citation:
Assignee:
SUNSHINE LAKE PHARMA CO LTD (CN)
International Classes:
C07D491/044; A61K31/42; A61K31/4353; A61P1/00; A61P1/04; A61P1/16; A61P3/00; A61P3/06; A61P3/10; A61P9/00; A61P9/04; A61P9/10; A61P9/12; A61P31/04; A61P31/20; A61P35/00
Foreign References:
| CN107686486A | 2018-02-13 | |||
| CN112876490A | 2021-06-01 | |||
| CN112876492A | 2021-06-01 | |||
| CN112876491A | 2021-06-01 | |||
| CN112876493A | 2021-06-01 |
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