Title:
NEW EPIDERMAL GROWTH FACTOR RECEPTOR INHIBITOR AND APPLICATION THEREOF
Document Type and Number:
WIPO Patent Application WO/2017/088746
Kind Code:
A1
Abstract:
An epidermal growth factor receptor inhibitor as shown in the following formula, a pharmaceutical composition containing the receptor inhibitor, and use of the inhibitor or the pharmaceutical composition as a medicine for preventing and/or treating cancers. The groups have definitions described in the description. The compound shows good EGFR inhibition activity especially for a mutational EGFR, thereby being expected to be a medicine which resists tumors, having drug resistance due to EGFR mutations, has a specific curative effect and is less in side effects.
Inventors:
WANG YONG (CN)
ZHANG XIAOMENG (CN)
ZHAO LIWEN (CN)
WANG XIAOWEI (CN)
HAN LUWEI (CN)
DAI XUEJUAN (CN)
ZHANG XIAOMENG (CN)
ZHAO LIWEN (CN)
WANG XIAOWEI (CN)
HAN LUWEI (CN)
DAI XUEJUAN (CN)
Application Number:
PCT/CN2016/106862
Publication Date:
June 01, 2017
Filing Date:
November 23, 2016
Export Citation:
Assignee:
NANJING SANHOME PHARMACEUTICAL CO LTD (CN)
International Classes:
C07D471/04; A61K31/506; A61K31/5383; A61K31/542; A61P35/00; C07D487/04; C07D498/04; C07D513/04
Domestic Patent References:
| WO2016173438A1 | 2016-11-03 | |||
| WO2015003658A1 | 2015-01-15 |
Foreign References:
| CN103570731A | 2014-02-12 | |||
| CN103702990A | 2014-04-02 |
Attorney, Agent or Firm:
NANJING TIANHUA PATENT AGENT CO., LTD. (CN)
Download PDF:
Previous Patent: INFORMATION PROCESSING METHOD AND APPARATUS, AND ELECTRONIC DEVICE
Next Patent: ROTARY FURNACE
Next Patent: ROTARY FURNACE