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Patent Searching and Data


Title:
NEW INFLUENZA A VIRUS MAMMALIAN CELL ADAPTED STRAIN AND PREPARATION AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2016/134678
Kind Code:
A1
Abstract:
Disclosed is a new influenza A virus mammalian cell adapted strain and a preparation and use thereof. In particular, the adapted strain mutates position 86 of an NS2 protein of a PR8 virus strain from K to R. The growth ability of the obtained virus strain to be grown on the Vero cells is enhanced, and the virulence of the adapted strain in vivo is not enhanced.

Inventors:
SUN BING (CN)
XU KE (CN)
ZHANG HONG (CN)
Application Number:
PCT/CN2016/074850
Publication Date:
September 01, 2016
Filing Date:
February 29, 2016
Export Citation:
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Assignee:
INST PASTEUR OF SHANGHAI CHINESE ACAD OF SCIENCES (CN)
International Classes:
C07K14/11; C12N5/10; C12N7/00; C12N15/44; C12N15/85; C12R1/93
Foreign References:
US20110081373A12011-04-07
CN102304495A2012-01-04
CN1976717A2007-06-06
Attorney, Agent or Firm:
XU & PARTNERS,LLC. (CN)
上海一平知识产权代理有限公司 (CN)
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