Title:
NEW METHOD FOR PREPARING ALISKIREN INTERMEDIATE
Document Type and Number:
WIPO Patent Application WO/2017/143627
Kind Code:
A1
Abstract:
The present application relates to a method for preparing an Aliskiren intermediate (III). The Aliskiren intermediate is prepared by carrying out a reduction reaction of a compound (IV) with sodium borohydride and boron trifluoride tetrahydrofuran.
Inventors:
JIN GUANGYU (CN)
Application Number:
PCT/CN2016/075531
Publication Date:
August 31, 2017
Filing Date:
March 03, 2016
Export Citation:
Assignee:
CHANGZHOU PHARMACEUTICAL FACTORY CO LTD (CN)
International Classes:
C07C41/26; C07C43/253
Domestic Patent References:
| WO2011148392A1 | 2011-12-01 |
Other References:
WANG, F. ET AL.: "An Improved and Economical Process for the Manufacture of the Key Intermediate of Aliskiren, a New Potent Renin Inhibitor", ORGANIC PROCESS RESEARCH & DEVELOPMENT, vol. 17, no. 11, 7 October 2013 (2013-10-07), pages 1458 - 1462, XP055412899
Attorney, Agent or Firm:
NANJING JINGWEI PATENT & TRADEMARK AGENCY CO., LTD (CN)
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