Title:
NEW PI3K KINASE INHIBITOR
Document Type and Number:
WIPO Patent Application WO/2016/101553
Kind Code:
A1
Abstract:
The present invention relates to a PI3K kinase inhibitor, comprising a compound of a formula I or pharmaceutically acceptable salts, solvate, ester, acid, metabolite, or a prodrug thereof, Y, W, Z, R1, R2, R3, and R4 being defined in the specification. The present invention further relates to a pharmaceutical composition of the compound of the formula I and a usage of the pharmaceutical composition in preparing drugs used to treat diseases mediated by PI3K kinase activation.
Inventors:
LIU QINGSONG (CN)
LIU JING (CN)
ZHANG XIN (CN)
LIANG XIAOFEI (CN)
LIU XIAOCHUAN (CN)
LIU JUANJUAN (CN)
CHEN CHENG (CN)
ZHAO ZHENG (CN)
WANG AOLI (CN)
WANG WENCHAO (CN)
WU HONG (CN)
WANG BEILEI (CN)
WANG LI (CN)
LIU JING (CN)
ZHANG XIN (CN)
LIANG XIAOFEI (CN)
LIU XIAOCHUAN (CN)
LIU JUANJUAN (CN)
CHEN CHENG (CN)
ZHAO ZHENG (CN)
WANG AOLI (CN)
WANG WENCHAO (CN)
WU HONG (CN)
WANG BEILEI (CN)
WANG LI (CN)
Application Number:
PCT/CN2015/081240
Publication Date:
June 30, 2016
Filing Date:
June 11, 2015
Export Citation:
Assignee:
HEFEI INST PHYSICAL SCI CAS (CN)
HEFEI COSOURCE PHARMACEUTICAL CO LTD (CN)
HEFEI COSOURCE PHARMACEUTICAL CO LTD (CN)
International Classes:
C07D417/04; A61K31/4439; A61K31/444; A61K31/506; A61P1/04; A61P3/04; A61P3/10; A61P9/10; A61P9/12; A61P11/00; A61P11/06; A61P13/08; A61P17/00; A61P17/06; A61P19/02; A61P25/28; A61P29/00; A61P31/22; A61P35/00; A61P35/02; A61P37/06; C07D417/14
Domestic Patent References:
| WO2013052845A1 | 2013-04-11 |
Foreign References:
| CN102149711A | 2011-08-10 | |||
| CN101098869A | 2008-01-02 | |||
| CN101331125A | 2008-12-24 | |||
| CN101484452A | 2009-07-15 |
Attorney, Agent or Firm:
SHANGCHENG & PARTNERS (CN)
北京尚诚知识产权代理有限公司 (CN)
北京尚诚知识产权代理有限公司 (CN)
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