Title:
A NEW POLYPEPTIDE-HUMAN NAD-DEPENDENT 2-HYDROXY ACID DEHYDROGENASE FAMILY PROTEIN 11 AND THE POLYNUCLEOTIDE ENCODING IT
Document Type and Number:
WIPO Patent Application WO/2001/072981
Kind Code:
A1
Abstract:
The present invention discloses a new polypeptide-human NAD-dependent 2-hydroxy acid dehydrogenase family protein 11, the polynucleotide enconding it and a method producing the polypeptide by DNA recombinant technology. The present invention further discloses a method of treating various disorders, e.g., malignant neoplasm, hematopathy, HIV infection and immunological disease and various inflammations etc. The present invention also disclose an antagonist of the polypeptide and its therapeutic action. The present invention further discloses the use of the polynucleotide encoding the new human NAD-dependent 2-hydroxy acid dehydrogenase family protein 11.
Inventors:
MAO YUMIN (CN)
XIE YI (CN)
XIE YI (CN)
Application Number:
PCT/CN2001/000459
Publication Date:
October 04, 2001
Filing Date:
March 26, 2001
Export Citation:
Assignee:
SHANGHAI BIOWINDOW GENE DEV (CN)
MAO YUMIN (CN)
XIE YI (CN)
MAO YUMIN (CN)
XIE YI (CN)
International Classes:
C12N9/04; A61K38/00; (IPC1-7): C12N9/02; A61K38/17; A61P35/00; A61P37/00; C07K14/435; C07K14/47; C12N15/12; C12N15/63; C12N15/85
Domestic Patent References:
| WO1998031815A2 | 1998-07-23 |
Foreign References:
| US5925543A | 1999-07-20 | |||
| US5976804A | 1999-11-02 |
Other References:
NEOTE K. ET AL.: "Characterization of the human HEXB gene encoding lysosomal beta-hexosaminidase", GENOMICS, vol. 3, no. 4, 1988, pages 279 - 286
Attorney, Agent or Firm:
SHANGHAI HUA DONG PATENT AGENCY (319 Yue Yang Road Shanghai 1, CN)
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