Title:
NEW PYRAZINE DERIVATIVE, AND PREPARATION METHOD AND MEDICAL APPLICATION THEREOF
Document Type and Number:
WIPO Patent Application WO/2017/004966
Kind Code:
A1
Abstract:
The present invention relates to a new pyrazine derivative, and preparation method and medical application thereof. The pyrazine derivative can remove a free radical, suppress calcium overload, has an effect of protecting cells, and is used to prevent or cure cardiovascular and cerebrovascular diseases, neurodegeneration diseases, and other related diseases.
Inventors:
WANG YUQIANG (CN)
YU PEI (CN)
SUN YEWEI (CN)
SHAN LUCHEN (CN)
ZHANG GAOXIAO (CN)
ZHANG ZAIJUN (CN)
YI PENG (CN)
YU PEI (CN)
SUN YEWEI (CN)
SHAN LUCHEN (CN)
ZHANG GAOXIAO (CN)
ZHANG ZAIJUN (CN)
YI PENG (CN)
Application Number:
PCT/CN2016/000360
Publication Date:
January 12, 2017
Filing Date:
July 04, 2016
Export Citation:
Assignee:
GUANGZHOU MAGPIE PHARMACEUTICAL CO LTD (CN)
International Classes:
A61K31/497; C07D241/12; A61P7/02; A61P9/00; A61P9/10; A61P11/00; A61P21/00; A61P21/04; A61P25/14; A61P25/16; A61P25/28; A61P27/06
Foreign References:
| CN105017165A | 2015-11-04 | |||
| CN102311396A | 2012-01-11 | |||
| CN102090412A | 2011-06-15 | |||
| CN101362724A | 2009-02-11 | |||
| CN102212008A | 2011-10-12 | |||
| CN102786484A | 2012-11-21 | |||
| CN101786992A | 2010-07-28 |
Other References:
See also references of EP 3321259A4
Attorney, Agent or Firm:
PANTERRAIN IP ATTORNEYS (CN)
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