Title:
NEW RESORCINARENE-BASED AMPHIPATHIC COMPOUND AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2018/079951
Kind Code:
A3
Abstract:
The present invention relates to a newly developed resorcinarene-based amphipathic compound, a method for producing the same, and a method for extracting, solubilizing, stabilizing, crystallizing, or analyzing a membrane protein by using the same. In addition, compared to a conventional compound, the compound can efficiently extract from a cell membrane, membrane proteins having a greater variety of structures and characteristics, and can stably store such membrane proteins for a long time in an aqueous solution. Therefore, the compound can be used to analyze the functions and structures of such membrane proteins. Analysis of the structures and functions of membrane proteins, being closely related to the development of new drugs, is one of the fields of greatest interest in biology and chemistry today.
Inventors:
CHAE PIL SEOK (KR)
HUSSAIN HAZRAT (KR)
HUSSAIN HAZRAT (KR)
Application Number:
PCT/KR2017/002871
Publication Date:
August 02, 2018
Filing Date:
March 17, 2017
Export Citation:
Assignee:
IUCF HYU ERICA CAMPUS (KR)
International Classes:
C07H15/18; C07K1/113; C07K1/14; C07K1/30; C07K14/705; G01N33/68; B82Y5/00
Domestic Patent References:
WO2015158575A1 | 2015-10-22 | |||
WO2004036315A1 | 2004-04-29 |
Other References:
CURTIS, A. D. M.: "Novel Calix [4] Resorcinarene Glycosides", TETRAHEDRON LETTERS, vol. 38, no. 24, 16 June 1997 (1997-06-16), pages 4295 - 4296, XP004074815
SAKAMIZU, T. ET AL.: "Structural Design of Resin Matrix and Acid-labile Dissolution Inhibitor of Chemical Amplification Positive Electron-beam Resist for Gigabit Lithography", JOURNAL OF PHOTOPOLYMER SCIENCE AND TECHNOLOGY, vol. 11, no. 4, 1998, pages 547 - 552, XP055524185
HUSAIN, A. A. ET AL.: "Spatially Directional Resorcin[4]arene Cavitand Glycoconjugates for Organic Catalysis", CHEMISTRY-A EUROPEAN JOURNAL, vol. 22, no. 18, 21 March 2016 (2016-03-21), pages 6223 - 6227, XP055524187
SAKAMIZU, T. ET AL.: "Structural Design of Resin Matrix and Acid-labile Dissolution Inhibitor of Chemical Amplification Positive Electron-beam Resist for Gigabit Lithography", JOURNAL OF PHOTOPOLYMER SCIENCE AND TECHNOLOGY, vol. 11, no. 4, 1998, pages 547 - 552, XP055524185
HUSAIN, A. A. ET AL.: "Spatially Directional Resorcin[4]arene Cavitand Glycoconjugates for Organic Catalysis", CHEMISTRY-A EUROPEAN JOURNAL, vol. 22, no. 18, 21 March 2016 (2016-03-21), pages 6223 - 6227, XP055524187
Attorney, Agent or Firm:
DANA PATENT LAW FIRM (KR)
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