Title:
NEW TYPE OF CYTIDINE DERIVATIVE DIMER AND APPLICATION THEREOF
Document Type and Number:
WIPO Patent Application WO/2016/078163
Kind Code:
A1
Abstract:
The present invention provides the cytidine derivative dimer of general formula (I), and an application thereof. The cytidine derivative dimer has a significant inhibitory effect on human colon cancer HCT-116 tumor cells, and has a strong inhibitory effect on transplanted human colon cancer HCT-116 tumors borne by nude mice. The cytidine derivative dimer of the present invention has strong antitumor activity and low toxicity.
Inventors:
YANG DARIA (CN)
WANG HAIDONG (CN)
WANG HUIJUAN (CN)
LIEW SIONG TERN (CN)
WANG HAIDONG (CN)
WANG HUIJUAN (CN)
LIEW SIONG TERN (CN)
Application Number:
PCT/CN2014/093220
Publication Date:
May 26, 2016
Filing Date:
December 08, 2014
Export Citation:
Assignee:
CHANGZHOU FANGYUAN PHARMACEUTICAL CO LTD (CN)
CHANGZHOU UPER BIOPHARMACEUTICAL CO LTD (CN)
CHANGZHOU UPER BIOPHARMACEUTICAL CO LTD (CN)
International Classes:
C07H1/00; A61K31/7068; A61P35/00; A61P35/02; A61P35/04; C07H19/06
Foreign References:
| CN101044150A | 2007-09-26 |
Attorney, Agent or Firm:
CHANGZHOU JIANGHAI YANGGUANG INTELLECTUAL PROPERTY AGENCY LTD. (CN)
常州市江海阳光知识产权代理有限公司 (CN)
常州市江海阳光知识产权代理有限公司 (CN)
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