Title:
NEW USE OF AMLEXANOX
Document Type and Number:
WIPO Patent Application WO/2018/059207
Kind Code:
A1
Abstract:
Disclosed is use of amlexanox or a salt thereof or a solvate thereof in preparation of a drug having an inhibitory action on the smooth muscle cells, in particular a drug for preventing and treating vascular restenosis. Further disclosed is a medical device, particularly a drug stent, the surface of which is distributed with amlexanox or the salt thereof or the pharmaceutical composition thereof. Amlexanox has an activity in inhibition of the proliferation of smooth muscle cells, has a low inhibitory property of the endothelial cell growth, is particularly suitable for applying on a medical device to prevent the incidence of vascular restenosis, while not delaying the repair of endothelium.
Inventors:
CHEN LU (CN)
LI JUNFEI (CN)
CHEN FEI (CN)
CHENG XIAO (CN)
LI JUNFEI (CN)
CHEN FEI (CN)
CHENG XIAO (CN)
Application Number:
PCT/CN2017/100885
Publication Date:
April 05, 2018
Filing Date:
September 07, 2017
Export Citation:
Assignee:
SHANGHAI MICROPORT MEDICAL GROUP CO LTD (CN)
International Classes:
A61K31/436; A61L27/54; A61L29/16; A61L31/16; A61P9/00; A61P9/10
Domestic Patent References:
| WO2009007673A2 | 2009-01-15 |
Foreign References:
| CN102137642A | 2011-07-27 |
Other References:
See also references of EP 3520789A4
Attorney, Agent or Firm:
SHANGHAI SAVVY INTELLECTUAL PROPERTY AGENCY (CN)
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