NEW USE OF COMPLEX OF ANGIOTENSIN II RECEPTOR ANTAGONIST METABOLITE AND NEP INHIBITOR

Title:

NEW USE OF COMPLEX OF ANGIOTENSIN II RECEPTOR ANTAGONIST METABOLITE AND NEP INHIBITOR

Document Type and Number:

WIPO Patent Application WO/2020/238884

Kind Code:

A1

Abstract:

The present invention belongs to the technical field of pharmaceutical applications, relates to new use of a complex of an angiotensin II receptor antagonist metabolite and a NEP inhibitor, and particularly relates to use of the complex in the preparation of a medicament for salt-sensitive hypertension.

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Inventors:

SUN JINGCHAO (CN)
JING XIAOLONG (CN)
XIAO YING (CN)

Application Number:

PCT/CN2020/092256

Publication Date:

December 03, 2020

Filing Date:

May 26, 2020

Export Citation:

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Assignee:

SHENZHEN SALUBRIS PHARM CO LTD (CN)

International Classes:

C07D403/10; A61K31/216; A61K31/41; A61K31/4178; A61P9/04; A61P9/12

Domestic Patent References:

WO2017125031A1	2017-07-27
WO2007056546A1	2007-05-18

Foreign References:

CN105963296A	2016-09-28
CN105669581A	2016-06-15
CN106138041A	2016-11-23
CN105960398A	2016-09-21

Other References:

TZUNG-DAU WANG ET AL.: "Effects of Sacubitril/Valsartan (LCZ696) on Natriuresis, DiuresiBlood Pressures, and NT-proBNP in Salt-Sensitive Hypertension", HYPERTENSION, 31 January 2017 (2017-01-31), XP055762832, DOI: 20200714090129Y

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