Title:
NICOTINAMIDE VIRTUAL TEMPLATE SURFACE MOLECULARLY IMPRINTED MATERIAL AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF
Document Type and Number:
WIPO Patent Application WO/2021/103622
Kind Code:
A1
Abstract:
Disclosed are a nicotinamide virtual template surface molecularly imprinted material and a preparation method therefor and an application thereof, relating to the technical field of chemical materials. The preparation method comprises the steps of preparing a modified silica gel carrier, preparing the virtual template surface molecularly imprinted material, and the like. The method novelly uses the structural analogues nicotinamide of imidacloprid and acetamiprid as a virtual template to prepare a silica gel surface molecularly imprinted material, the pollution caused by template leakage can be avoided, imidacloprid and acetamiprid in a water-soluble tea extract can also be specifically removed, the removal rates of the imidacloprid and acetamiprid are respectively greater than 96% and 93%, and the loss of tea polyphenol in the extract is less than 10%. In addition, a molecularly imprinted adsorption column prepared can be eluted by an ethanol solution, the eluted adsorption column can be reused, so that the molecularly imprinted adsorption column can be well applied to a preparation process of the tea extract, and the application prospect is good.
Inventors:
WANG HONGXIN (CN)
CHEN JINGYU (CN)
WU SHIJIA (CN)
WEI XINLIN (CN)
HUANG XIN (CN)
WANG LI (CN)
CHEN JINGYU (CN)
WU SHIJIA (CN)
WEI XINLIN (CN)
HUANG XIN (CN)
WANG LI (CN)
Application Number:
PCT/CN2020/105396
Publication Date:
June 03, 2021
Filing Date:
July 29, 2020
Export Citation:
Assignee:
UNIV JIANGNAN (CN)
International Classes:
C08J9/26; B01D15/10; B01D15/22; B01J20/26; B01J20/30; C07C231/24; C07C237/06; C07D311/62; C08F220/06; C08F222/14; C08F292/00
Domestic Patent References:
| WO2013190506A1 | 2013-12-27 |
Foreign References:
| CN104892868A | 2015-09-09 | |||
| CN110951105A | 2020-04-03 | |||
| CN110511423A | 2019-11-29 | |||
| CN103478337A | 2014-01-01 |
Other References:
MIN-TING LI, YONG-YAN ZHU, LI LI, WEN-NA WANG, YONG-GUAN YIN, QUAN-HONG ZHU: "Molecularly imprinted polymers on a silica surface for the adsorption of tobacco-specific nitrosamines in mainstream cigarette smoke", JOURNAL OF SEPARATION SCIENCE, vol. 38, no. 14, 25 April 2015 (2015-04-25), pages 2551 - 2557, XP055814639, ISSN: 1615-9306, DOI: 10.1002/jssc.201500193
CHEN JINGYU , HUANG XIN , WANG LI , WANG HONGXIN: "Synthesis of Molecularly Imprinted Polymers of Virtual Template Surface and its Application on Simultaneously Remove Imidacloprid and Acetamiprid", FOOD AND FERMENTATION INDUSTRIES, vol. 46, no. 5, 11 December 2019 (2019-12-11), pages 91 - 97, XP055814645, DOI: 10.13995/j.cnki.11-1802/ts.022775
JINGYU CHEN, XIN HUANG, LI WANG, CHAOYANG MA, SHIJIA WU ,HONGXIN WANG: "Dummy template surface molecularly imprinted polymers based on silica gel for removing imidacloprid and acetamiprid in tea polyphenols", JOURNAL OF SEPARATION SCIENCE, vol. 43, no. 12, 25 March 2020 (2020-03-25), pages 2467 - 2476, XP055814655, ISSN: 1615-9306, DOI: 10.1002/jssc.201901268
LIANG XIAO-YUN , GUO ZHI-AN , WANG DAN-DAN , ZHAO JING-CHAN: "Preparation of Imidacloprid-Imprinted Polymer and its Application As a Aolid Phase Extract", CHINESE JOURNAL OF ANALYSIS LABORATORY, vol. 27, no. 5, 1 May 2008 (2008-05-01), CN, pages 9 - 12, XP055814658, ISSN: 1000-0720, DOI: 10.13595/j.ckni.issn.1000-0720.2008.0132
XIE LEI ,WU WAN-YI ,LI LU , XIE XIN-AN, LI YAN: "Determination of Pesticide Residues in Tea Broth by Solid Phase Extration Column of Dual Packing Materials with UV Spectrophotometry", SCIENCE AND TECHNOLOGY OF FOOD INDUSTRY, vol. 40, no. 20, 30 May 2019 (2019-05-30), pages 256 - 261, XP055814663, ISSN: 1002-0306, DOI: 10.13386/j.issn1002-0306.2019.20.041
CHEN JINGYU , HUANG XIN , WANG LI , WANG HONGXIN: "Synthesis of Molecularly Imprinted Polymers of Virtual Template Surface and its Application on Simultaneously Remove Imidacloprid and Acetamiprid", FOOD AND FERMENTATION INDUSTRIES, vol. 46, no. 5, 11 December 2019 (2019-12-11), pages 91 - 97, XP055814645, DOI: 10.13995/j.cnki.11-1802/ts.022775
JINGYU CHEN, XIN HUANG, LI WANG, CHAOYANG MA, SHIJIA WU ,HONGXIN WANG: "Dummy template surface molecularly imprinted polymers based on silica gel for removing imidacloprid and acetamiprid in tea polyphenols", JOURNAL OF SEPARATION SCIENCE, vol. 43, no. 12, 25 March 2020 (2020-03-25), pages 2467 - 2476, XP055814655, ISSN: 1615-9306, DOI: 10.1002/jssc.201901268
LIANG XIAO-YUN , GUO ZHI-AN , WANG DAN-DAN , ZHAO JING-CHAN: "Preparation of Imidacloprid-Imprinted Polymer and its Application As a Aolid Phase Extract", CHINESE JOURNAL OF ANALYSIS LABORATORY, vol. 27, no. 5, 1 May 2008 (2008-05-01), CN, pages 9 - 12, XP055814658, ISSN: 1000-0720, DOI: 10.13595/j.ckni.issn.1000-0720.2008.0132
XIE LEI ,WU WAN-YI ,LI LU , XIE XIN-AN, LI YAN: "Determination of Pesticide Residues in Tea Broth by Solid Phase Extration Column of Dual Packing Materials with UV Spectrophotometry", SCIENCE AND TECHNOLOGY OF FOOD INDUSTRY, vol. 40, no. 20, 30 May 2019 (2019-05-30), pages 256 - 261, XP055814663, ISSN: 1002-0306, DOI: 10.13386/j.issn1002-0306.2019.20.041
Attorney, Agent or Firm:
HARBIN SHINEIP INTELLECTUAL PROPERTY AGENCY CO., LTD. (CN)
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