Title:
NITRIC OXIDE RELEASING PRODRUGS OF MDA AND MDMA
Document Type and Number:
WIPO Patent Application WO/2023/129958
Kind Code:
A3
Abstract:
Provided herein are compounds of Formula (I), Formula (II), and Formula (III) or pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R4, R5, R6, R7 and A are defined herein. Also provided herein are pharmaceutical compositions comprising a compound of Formula (I), Formula (II), or Formula (III) and methods of using a compound of Formula (I), Formula (II), or Formula (III), e.g., in the treatment of a mental health disease or disorder.
Inventors:
SHORT GLENN (DE)
PERNI ROBERT B (DE)
KHAN TANWEER (DE)
PERNI ROBERT B (DE)
KHAN TANWEER (DE)
Application Number:
PCT/US2022/082468
Publication Date:
August 31, 2023
Filing Date:
December 28, 2022
Export Citation:
Assignee:
ATAI LIFE SCIENCES AG (DE)
International Classes:
A61K31/357; C07D317/06
Domestic Patent References:
| WO2023056102A1 | 2023-04-06 |
Foreign References:
| US4017636A | 1977-04-12 | |||
| US4937360A | 1990-06-26 |
Other References:
DATABASE PUBCHEM COMPOUND 13 February 2015 (2015-02-13), ANONYMOUS : "SCHEMBL10447288", XP093088059, retrieved from PUBCHEM Database accession no. 235735835
DATABASE PUBCHEM COMPOUND 14 October 2015 (2015-10-14), ANONYMOUS : "2-(benzo[d][1,3]dioxol-5- yl)ethanamine", XP093088062, retrieved from PUBCHEM Database accession no. 104098418
DATABASE PUBCHEM COMPOUND 13 November 2014 (2014-11-13), ANONYMOUS : "10554-64-0", XP093088066, retrieved from PUBCHEM Database accession no. 117678335
DATABASE PUBCHEM COMPOUND 14 October 2015 (2015-10-14), ANONYMOUS : "2-(benzo[d][1,3]dioxol-5- yl)ethanamine", XP093088062, retrieved from PUBCHEM Database accession no. 104098418
DATABASE PUBCHEM COMPOUND 13 November 2014 (2014-11-13), ANONYMOUS : "10554-64-0", XP093088066, retrieved from PUBCHEM Database accession no. 117678335
Attorney, Agent or Firm:
TUSCAN, Michael S. et al. (US)
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