NITROGEN-CONTAINING COMPOUND, COMPOSITION COMPRISING SAID NITROGEN-CONTAINING COMPOUND, AND MARKER FOR PREDICTING TUMOR GRADE

WIPO Patent Application WO/2024/075736

A1

The present invention addresses the problem of providing a nitrogen-containing compound effective for inhibiting cancer stem cell proliferation.　The problem is solved by a nitrogen-containing compound represented by general formula (I), or a pharmaceutically acceptable salt thereof: [Chemical formula 1] (here, m and n are the same or different and represent an integer of 1 to 3. R1 and R2 are the same or different and represent a hydrogen atom, a C1-6 linear or branched alkyl group optionally having a halogen atom as a substituent, a C1-6 linear or branched alkoxy group, a halogen atom, an amino group, a hydroxyl group, a nitro group, a carboxy group, or a cyano group. R3 represents a C1-6 branched or linear alkyl group optionally having a halogen atom as a substituent. X1, X2, and X3 represent a carbon atom or a nitrogen atom, and one or two of X1, X2, and X3 are nitrogen atoms. X4 represents a carbon atom or a nitrogen atom. However, excluding (i) the situation in which X1 and X4 are both nitrogen atoms and X2 and X3 are both carbon atoms and (ii) the situation in which X3 and X4 are both nitrogen atoms and X1 and X2 are both carbon atoms.).

HAYASHI MIKIO (JP)
IKEDA YOSHIKI (JP)
IWATA RYOICHI (JP)

PCT/JP2023/036077

April 11, 2024

October 03, 2023

Click for automatic bibliography generation  

KANSAI MEDICAL UNIV EDUCATIONAL CORPORATION (JP)

C07D401/12; A61K31/4439; A61K31/506; A61P11/00; A61P25/00; A61P35/00; A61P35/04; C07D401/14; C07D403/12

SAEGUSA & PARTNERS (JP)

View/Download PDF      PDF Help

Previous Patent: RFID MODULE

Next Patent: CATALYST COMPOSITION CONTAINING HYDROCARBON-BASED IONOMER AND FLUORINE-BASED RESIN, AND SOLID-STATE ...