Title:
NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND APPLICATIONS THEREOF
Document Type and Number:
WIPO Patent Application WO/2018/086585
Kind Code:
A1
Abstract:
Disclosed in the present invention are nitrogen-containing heterocyclic compounds, a preparation method therefor, a pharmaceutical composition thereof, and applications thereof. The nitrogen-containing heterocyclic compounds represented by formula II can be effectively combined with bromodomains of BRD4, BRD3, BRD2 and BRDT of a BET family, and play a specific role.
Inventors:
HU YONGHAN (CN)
CAI DONGMEI (CN)
DONG PING (CN)
ZHU JIUXIANG (CN)
LI MANHUA (CN)
DONG JIAQIANG (CN)
WANG TIELIN (CN)
CAI DONGMEI (CN)
DONG PING (CN)
ZHU JIUXIANG (CN)
LI MANHUA (CN)
DONG JIAQIANG (CN)
WANG TIELIN (CN)
Application Number:
PCT/CN2017/110438
Publication Date:
May 17, 2018
Filing Date:
November 10, 2017
Export Citation:
Assignee:
SHANDONG LUOXIN PHARMACY STOCK (CN)
LUOXIN BIOTECHNOLOGY SHANGHAI CO LTD (CN)
LUOXIN BIOTECHNOLOGY SHANGHAI CO LTD (CN)
International Classes:
C07D471/04; A61K31/404; A61K31/437; A61K31/5025; A61K31/517; A61P11/00; A61P29/00; C07D209/46; C07D209/48; C07D239/80; C07D487/04
Foreign References:
| CN105164127A | 2015-12-16 | |||
| CN105828820A | 2016-08-03 | |||
| CN105254635A | 2016-01-20 | |||
| CN104334526A | 2015-02-04 |
Attorney, Agent or Firm:
SHANGHAI BESHINING LAW OFFICE (CN)
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