NITROGEN-CONTAINING HETEROCYCLIC DERIVATIVE REGULATOR, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF

WIPO Patent Application WO/2023/061294

A1

Disclosed are a nitrogen-containing heterocyclic derivative regulator, a preparation method therefor and an application thereof. Particularly, disclosed are a compound as represented in general formula (I), a preparation method therefor, a pharmaceutical composition containing same, and use thereof as a KRAS G12D mutation regulator in the treatment of diseases or conditions such as tumors, wherein each substituent in general formula (I) is the same as the definition in the description.

JP6328145	FLAP regulator
JPH09176165	IMIDAZO(1,2-A)PYRIDINE DERIVATIVE AND ITS PRODUCTION AND USE
JPH10306083	CYCLIC UREA-BASED COMPOUND, PRODUCTION THEREOF AND AGROCHEMICAL MATERIAL

HE YONG (CN)
JIA LANQI (CN)
GU YUGUI (CN)
LU JUN (CN)
WU WENTING (CN)
LI SHANGFENG (CN)
LU XIAOJIE (CN)
LI JING (CN)

PCT/CN2022/124111

April 20, 2023

October 09, 2022

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ZAI LAB SHANGHAI CO LTD (CN)

C07D471/04; A61K31/517; A61K31/519; A61P35/00; C07D487/04; C07D498/04; C07D519/00

WO2022214102A1	2022-10-13
WO2022228568A1	2022-11-03
WO2022236578A1	2022-11-17
WO2022237649A1	2022-11-17
WO2022247760A1	2022-12-01
WO2022248885A2	2022-12-01
WO2022002102A1	2022-01-06
WO2022031678A1	2022-02-10
WO2022042630A1	2022-03-03
WO2022047260A1	2022-03-03
WO2022061251A1	2022-03-24
WO2022068921A1	2022-04-07
WO2022132200A1	2022-06-23
WO2022148422A1	2022-07-14
WO2022171147A1	2022-08-18
WO2022173870A1	2022-08-18
WO2022177917A2	2022-08-25
WO2022194191A1	2022-09-22
WO2021041671A1	2021-03-04
WO2020146613A1	2020-07-16

CN115304623A	2022-11-08
CN112110918A	2020-12-22

BEIJING CAI HE LAW FIRM (CN)

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